H James Stunden
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Explore the profile of H James Stunden including associated specialties, affiliations and a list of published articles.
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8
Citations
355
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Recent Articles
1.
Rolfes V, Secchim Ribeiro L, Hawwari I, Bottcher L, Rosero N, Maasewerd S, et al.
Cell Rep
. 2020 May;
31(6):107615.
PMID: 32402278
The inflammasomes control the bioactivity of pro-inflammatory cytokines of the interleukin (IL)-1 family. The inflammasome assembled by NLRP3 has been predominantly studied in homogeneous cell populations in vitro, neglecting the...
2.
Nejad C, Stunden H, Gantier M
FEBS J
. 2018 Apr;
285(20):3695-3716.
PMID: 29688631
The discovery of microRNAs (miRNAs) in the early 1990's has revolutionized our thinking of post-transcriptional gene control. miRNAs are involved in the regulation of almost every cellular and developmental process...
3.
Fulle L, Steiner N, Funke M, Gondorf F, Pfeiffer F, Siegl J, et al.
Mol Ther
. 2017 Nov;
26(1):95-104.
PMID: 29103909
The chemokine CCL17, mainly produced by dendritic cells (DCs) in the immune system, is involved in the pathogenesis of various inflammatory diseases. As a ligand of CCR4, CCL17 induces chemotaxis...
4.
Civit L, Taghdisi S, Jonczyk A, Hassel S, Grober C, Blank M, et al.
Biochimie
. 2017 Oct;
145:53-62.
PMID: 29054799
The sensitive and specific detection of pathogenic cells is essential in clinical diagnostics. To achieve this, molecular tools are required that unequivocally recognise appropriate cell surface molecules, such as biomarkers...
5.
Pepin G, Nejad C, Ferrand J, Thomas B, Stunden H, Sanij E, et al.
mBio
. 2017 Oct;
8(5).
PMID: 28974621
Inflammatory responses, while essential for pathogen clearance, can also be deleterious to the host. Chemical inhibition of topoisomerase 1 (Top1) by low-dose camptothecin (CPT) can suppress transcriptional induction of antiviral...
6.
Sarvestani S, Stunden H, Behlke M, Forster S, McCoy C, Tate M, et al.
Nucleic Acids Res
. 2014 Dec;
43(2):1177-88.
PMID: 25539920
Anti-microRNA (miRNA) oligonucleotides (AMOs) with 2'-O-Methyl (2'OMe) residues are commonly used to study miRNA function and can achieve high potency, with low cytotoxicity. Not withstanding this, we demonstrate the sequence-dependent...
7.
Stunden H, Latz E
Cell Res
. 2012 Sep;
23(2):168-70.
PMID: 22945351
Inflammasomes are multiprotein complexes that detect and respond to foreign and endogenous danger signals by activating caspase-1; active caspase-1, in turn, matures the pro-inflammatory IL-1β family cytokines by cleaving their...
8.
Gantier M, Stunden H, McCoy C, Behlke M, Wang D, Kaparakis-Liaskos M, et al.
Nucleic Acids Res
. 2012 Jun;
40(16):8048-58.
PMID: 22684508
Fine-tuning of inflammatory responses by microRNAs (miRNAs) is complex, as they can both enhance and repress expression of pro-inflammatory mediators. In this study, we investigate inflammatory responses following global miRNA...