Marc Beyer
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Explore the profile of Marc Beyer including associated specialties, affiliations and a list of published articles.
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138
Citations
6790
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Recent Articles
1.
Beckroge T, Jux B, Seifert H, Theobald H, De Domenico E, Paulusch S, et al.
Life Sci Alliance
. 2025 Feb;
8(4).
PMID: 39909558
The transition of an embryo from gastrulation to organogenesis requires precisely coordinated changes in gene expression, but the underlying mechanisms remain unclear. The RNA-binding protein Trim71 is essential for development...
2.
Wischhof L, Mathew A, Bonaguro L, Beyer M, Ehninger D, Nicotera P, et al.
Sci Rep
. 2024 Nov;
14(1):27182.
PMID: 39516523
Inhibition of the mitochondrial oxidative phosphorylation (OXPHOS) system can lead to metabolic disorders and neurodegenerative diseases. In primary mitochondrial disorders, reactive astrocytes often accompany neuronal degeneration and may contribute to...
3.
Zatcepin A, Gnorich J, Rauchmann B, Bartos L, Wagner S, Franzmeier N, et al.
Mol Neurodegener
. 2024 Sep;
19(1):64.
PMID: 39238030
Background: Microglial activation is one hallmark of Alzheimer disease (AD) neuropathology but the impact of the regional interplay of microglia cells in the brain is poorly understood. We hypothesized that...
4.
Grass T, Dokuzluoglu Z, Buchner F, Rosignol I, Thomas J, Caldarelli A, et al.
Cell Rep Med
. 2024 Jul;
5(8):101659.
PMID: 39067446
Whether neurodevelopmental defects underlie postnatal neuronal death in neurodegeneration is an intriguing hypothesis only recently explored. Here, we focus on spinal muscular atrophy (SMA), a neuromuscular disorder caused by reduced...
5.
Seep L, Grein S, Splichalova I, Ran D, Mikhael M, Hildebrand S, et al.
Sci Data
. 2024 May;
11(1):524.
PMID: 38778016
Datasets consist of measurement data and metadata. Metadata provides context, essential for understanding and (re-)using data. Various metadata standards exist for different methods, systems and contexts. However, relevant information resides...
6.
Kayvanjoo A, Splichalova I, Bejarano D, Huang H, Mauel K, Makdissi N, et al.
Elife
. 2024 Mar;
13.
PMID: 38526524
During embryogenesis, the fetal liver becomes the main hematopoietic organ, where stem and progenitor cells as well as immature and mature immune cells form an intricate cellular network. Hematopoietic stem...
7.
Scholz R, Brosamle D, Yuan X, Beyer M, Neher J
Immunol Rev
. 2024 Mar;
323(1):209-226.
PMID: 38491845
Microglia, the major population of brain-resident macrophages, are now recognized as a heterogeneous population comprising several cell subtypes with different (so far mostly supposed) functions in health and disease. A...
8.
Leidner J, Theis H, Kraut M, Ragogna A, Beyer M, Schultze J, et al.
J Vis Exp
. 2024 Mar;
(204).
PMID: 38465925
Transcriptomics allows to obtain comprehensive insights into cellular programs and their responses to perturbations. Despite a significant decrease in the costs of library production and sequencing in the last decade,...
9.
Chang Y, Bach L, Hasiuk M, Wen L, Elmzzahi T, Tsui C, et al.
Sci Immunol
. 2024 Mar;
9(93):eadd4818.
PMID: 38427718
T follicular helper (T) cells are essential for effective antibody responses, but deciphering the intrinsic wiring of mouse T cells has long been hampered by the lack of a reliable...
10.
Torres S, Man K, Elmzzahi T, Malko D, Chisanga D, Liao Y, et al.
Nat Immunol
. 2024 Feb;
25(3):496-511.
PMID: 38356058
Visceral adipose tissue (VAT) is an energy store and endocrine organ critical for metabolic homeostasis. Regulatory T (T) cells restrain inflammation to preserve VAT homeostasis and glucose tolerance. Here, we...