Bryan R G Williams
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Explore the profile of Bryan R G Williams including associated specialties, affiliations and a list of published articles.
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150
Citations
7117
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Recent Articles
1.
Fernando D, Ahmed A, Williams B
Front Oncol
. 2024 Mar;
14:1347694.
PMID: 38525424
Pediatric high-grade gliomas (pHGG) are a rare yet devastating malignancy of the central nervous system's glial support cells, affecting children, adolescents, and young adults. Tumors of the central nervous system...
2.
Ahmed A, Almasabi S, Firestein R, Williams B
Front Immunol
. 2023 Dec;
14:1270194.
PMID: 38077324
Colorectal cancer (CRC) is one of the most common forms of cancer worldwide and treatment options for advanced CRC, which has a low 5-year survival rate, remain limited. Integrin-linked kinase...
3.
Ganju V, Marx G, Pattison S, Amaro-Mugridge N, Zhao J, Williams B, et al.
Clin Cancer Res
. 2023 Nov;
30(2):304-314.
PMID: 37976042
Purpose: We assessed the safety and efficacy of an EGFR-targeted, super-cytotoxic drug, PNU-159682-packaged nanocells with α-galactosyl ceramide-packaged nanocells (E-EDV-D682/GC) in patients with advanced pancreatic ductal adenocarcinoma (PDAC) who had exhausted...
4.
Chueh A, Tse J, Dickinson M, Ioannidis P, Jenkins L, Togel L, et al.
Clin Cancer Res
. 2023 Sep;
29(18):3826.
PMID: 37712140
No abstract available.
5.
Gao S, Amaro-Mugridge N, Madrid-Weiss J, Petkovic N, Vanegas N, Visvanathan K, et al.
Front Immunol
. 2023 Feb;
13:1038562.
PMID: 36818474
Most current anti-viral vaccines elicit a humoral and cellular immune response the pathway of phagocytic cell mediated viral antigen presentation to B and T cell surface receptors. However, this pathway...
6.
Ullah T, Balka K, Ambrose R, Pepin G, Wilce M, Wilce J, et al.
mBio
. 2022 Aug;
13(4):e0206422.
PMID: 35924852
Cytoplasmic detection of DNA by cyclic GMP-AMP (cGAMP) synthase (cGAS) is an essential component of antiviral responses. Upon synthesis, cGAMP binds to the stimulator of interferon (IFN) genes (STING) in...
7.
Almasabi S, Boyd R, Ahmed A, Williams B
Front Oncol
. 2022 Jun;
12:836005.
PMID: 35692780
Integrin-linked kinase (ILK) has been implicated as a molecular driver and mediator in both inflammation and tumorigenesis of the colon. However, a role for ILK in the tumor microenvironment (TME)...
8.
Almasabi S, Ahmed A, Boyd R, Williams B
Front Genet
. 2021 Jun;
12:638558.
PMID: 34163519
Integrin-linked kinase (ILK) has been implicated as a molecular driver and mediator in both inflammation and tumorigenesis of the colon. ILK functions as an adaptor and mediator protein linking the...
9.
Dowling J, Afzal R, Gearing L, Cervantes-Silva M, Annett S, Davis G, et al.
Nat Commun
. 2021 Mar;
12(1):1460.
PMID: 33674584
Mitochondria are important regulators of macrophage polarisation. Here, we show that arginase-2 (Arg2) is a microRNA-155 (miR-155) and interleukin-10 (IL-10) regulated protein localized at the mitochondria in inflammatory macrophages, and...
10.
Pepin G, De Nardo D, Rootes C, Ullah T, Al-Asmari S, Balka K, et al.
mBio
. 2020 Jan;
11(1).
PMID: 31992625
Activation of cyclic GMP-AMP (cGAMP) synthase (cGAS) plays a critical role in antiviral responses to many DNA viruses. Sensing of cytosolic DNA by cGAS results in synthesis of the endogenous...