Guy Salvesen
Overview
Explore the profile of Guy Salvesen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
19
Citations
2441
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Bibo-Verdugo B, Salvesen G
Int J Mol Sci
. 2024 May;
25(10).
PMID: 38791309
The protein scaffold that includes the caspases is ancient and found in all domains of life. However, the stringent specificity that defines the caspase biologic function is relatively recent and...
2.
Janiszewski T, Kolt S, Kaiserman D, Snipas S, Li S, Kulbacka J, et al.
J Biol Chem
. 2020 May;
295(28):9567-9582.
PMID: 32439802
Natural killer (NK) cells are key innate immunity effectors that combat viral infections and control several cancer types. For their immune function, human NK cells rely largely on five different...
3.
Kolt S, Janiszewski T, Kaiserman D, Modrzycka S, Snipas S, Salvesen G, et al.
J Med Chem
. 2020 Mar;
63(6):3359-3369.
PMID: 32142286
Cytotoxic T-lymphocytes (CTLs) and natural killer cells (NKs) kill compromised cells to defend against tumor and viral infections. Both effector cell types use multiple strategies to induce target cell death...
4.
Poreba M, Salvesen G
Cell Chem Biol
. 2017 May;
24(5):550-552.
PMID: 28525771
In a recent issue of Cell Chemical Biology, Taabazuing et al. (2017) reveal a bidirectional interplay between pathways leading to apoptosis and pyroptosis, two forms of regulated cell death with...
5.
Lee P, Zhu Z, Hachmann J, Nojima T, Kitamura D, Salvesen G, et al.
J Immunol
. 2016 Dec;
198(3):1066-1080.
PMID: 28031341
During a T cell-dependent immune response, formation of the germinal center (GC) is essential for the generation of high-affinity plasma cells and memory B cells. The canonical NF-κB pathway has...
6.
Fasci D, Anania V, Lill J, Salvesen G
Sci Signal
. 2016 Aug;
9(440):tc2.
PMID: 27507652
Arsenic trioxide chemotherapy cures acute promyelocytic leukemia by inducing the ubiquitylation of an oncogenic fusion protein containing promyelocytic leukemia protein (PML) subsequent to modification of PML by SUMO1 and SUMO2....
7.
Brumatti G, Ma C, Lalaoui N, Nguyen N, Navarro M, Tanzer M, et al.
Sci Transl Med
. 2016 May;
8(339):339ra69.
PMID: 27194727
Resistance to chemotherapy is a major problem in cancer treatment, and it is frequently associated with failure of tumor cells to undergo apoptosis. Birinapant, a clinical SMAC mimetic, had been...
8.
Oroz-Parra I, Navarro M, Cervantes-Luevano K, Alvarez-Delgado C, Salvesen G, Sanchez-Campos L, et al.
Toxins (Basel)
. 2016 Feb;
8(2):38.
PMID: 26861394
Lung cancer is one of the most common types of cancer in men and women and a leading cause of death worldwide resulting in more than one million deaths per...
9.
Park G, Tan J, Garcia G, Kang Y, Salvesen G, Zhang Z
J Biol Chem
. 2015 Dec;
291(7):3531-40.
PMID: 26699403
Parkinson disease (PD) is the most common age-dependent neurodegenerative movement disorder. Accumulated evidence indicates both environmental and genetic factors play important roles in PD pathogenesis, but the potential interaction between...
10.
Rajkovic J, Poreba M, Caglic D, Vidmar R, Wilk A, Borowik A, et al.
J Biol Chem
. 2015 Oct;
290(47):28231-28244.
PMID: 26446788
The genome of the parasite Trypanosoma cruzi encodes two copies of autophagy-related cysteine proteases, Atg4.1 and Atg4.2. T. cruzi autophagin-2 (TcAtg4.2) carries the majority of proteolytic activity and is responsible...