Sonia Kolt
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Explore the profile of Sonia Kolt including associated specialties, affiliations and a list of published articles.
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11
Citations
104
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Recent Articles
1.
Kasperkiewicz P, Kolt S, Janiszewski T, Skowron P, Krefft D, Brodzik R, et al.
Biochimie
. 2024 Jul;
226:91-98.
PMID: 38971457
Proteases catalyze hydrolysis of amide bonds within peptides and proteins, therefore they play crucial functions for organism functioning, but also in industry to facilitate numerous processes. Feather-degrading fungus Onygena corvina...
2.
Modrzycka S, Kolt S, Adams T, Potoczek S, Huntington J, Kasperkiewicz P, et al.
J Med Chem
. 2023 Mar;
66(6):3785-3797.
PMID: 36898159
Anticoagulation therapy is a mainstay of the treatment of thrombotic disorders; however, conventional anticoagulants trade antithrombotic benefits for bleeding risk. Factor (f) XI deficiency, known as hemophilia C, rarely causes...
3.
Groborz K, Kalinka M, Grzymska J, Kolt S, Snipas S, Poreba M
Chem Sci
. 2023 Mar;
14(9):2289-2302.
PMID: 36873853
Activated effector caspases 3, 6 and 7 are responsible for cleaving a number of target substrates, leading to the ultimate destruction of cells apoptosis. The functions of caspases 3 and...
4.
Janiszewski T, Kolt S, Ciaston I, Vizovisek M, Poreba M, Turk B, et al.
Cell Chem Biol
. 2023 Jan;
30(2):159-174.e8.
PMID: 36696904
Cathepsin K (CatK) is a lysosomal cysteine protease whose highest expression is found in osteoclasts, which are the cells responsible for bone resorption. Investigations of the functions and physiological relevance...
5.
Modrzycka S, Kolt S, Polderdijk S, Adams T, Potoczek S, Huntington J, et al.
Chem Sci
. 2022 Jul;
13(23):6813-6829.
PMID: 35774156
Activated protein C (APC), thrombin, and factor (f) Xa are vitamin K-dependent serine proteases that are key factors in blood coagulation. Moreover, they play important roles in inflammation, apoptosis, fibrosis,...
6.
Kasperkiewicz P, Hempel A, Janiszewski T, Kolt S, Snipas S, Drag M, et al.
J Biol Chem
. 2021 Jan;
295(51):17624-17631.
PMID: 33454002
Neutrophils are primary host innate immune cells defending against pathogens. One proposed mechanism by which neutrophils prevent the spread of pathogens is NETosis, the extrusion of cellular DNA resulting in...
7.
Bibo-Verdugo B, Snipas S, Kolt S, Poreba M, Salvesen G
J Biol Chem
. 2020 Jun;
295(32):11292-11302.
PMID: 32554464
Pyroptosis is the caspase-dependent inflammatory cell death mechanism that underpins the innate immune response against pathogens and is dysregulated in inflammatory disorders. Pyroptosis occurs via two pathways: the canonical pathway,...
8.
Janiszewski T, Kolt S, Kaiserman D, Snipas S, Li S, Kulbacka J, et al.
J Biol Chem
. 2020 May;
295(28):9567-9582.
PMID: 32439802
Natural killer (NK) cells are key innate immunity effectors that combat viral infections and control several cancer types. For their immune function, human NK cells rely largely on five different...
9.
Kolt S, Janiszewski T, Kaiserman D, Modrzycka S, Snipas S, Salvesen G, et al.
J Med Chem
. 2020 Mar;
63(6):3359-3369.
PMID: 32142286
Cytotoxic T-lymphocytes (CTLs) and natural killer cells (NKs) kill compromised cells to defend against tumor and viral infections. Both effector cell types use multiple strategies to induce target cell death...
10.
Groborz K, Kolt S, Kasperkiewicz P, Drag M
Biochimie
. 2019 May;
166:103-111.
PMID: 31103725
Cathepsin G is one of four members of the neutrophil serine protease family and constitutes an important biological target in various human inflammatory diseases, such as chronic obstructive pulmonary disease,...