Grahame Kidd
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Explore the profile of Grahame Kidd including associated specialties, affiliations and a list of published articles.
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15
Citations
2476
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Recent Articles
1.
Pal A, Lin C, Boykov I, Benson E, Kidd G, Fisher-Wellman K, et al.
Nutrients
. 2023 Nov;
15(22).
PMID: 38004202
Diet-induced obesity impairs mitochondrial respiratory responses in tissues that are highly metabolically active, such as the heart. However, less is known about the impact of obesity on the respiratory activity...
2.
Xu Z, Foster J, Lashley R, Wang X, Benson E, Kidd G, et al.
Front Cell Neurosci
. 2023 Sep;
17:1229731.
PMID: 37671169
Introduction: We previously discovered a pyridazine derivative compound series that can improve cognitive functions in mouse models of Alzheimer's disease. One of the advanced compounds from this series, LDN/OSU-0215111-M3, was...
3.
Aten S, Kiyoshi C, Arzola E, Patterson J, Taylor A, Du Y, et al.
Prog Neurobiol
. 2022 Mar;
213:102264.
PMID: 35283239
The complexity of astrocyte morphology and syncytial coupling through gap junctions are crucial for astrocyte function in the brain. However, the ultrastructural details of astrocyte arborization and interactions between neighboring...
4.
Duncan I, Radcliff A, Heidari M, Kidd G, August B, Wierenga L
Proc Natl Acad Sci U S A
. 2018 Nov;
115(50):E11807-E11816.
PMID: 30487224
Endogenous remyelination of the CNS can be robust and restore function, yet in multiple sclerosis it becomes less complete with time. Promoting remyelination is a major therapeutic goal, both to...
5.
He X, Zhang L, Queme L, Liu X, Lu A, Waclaw R, et al.
Nat Med
. 2018 Feb;
24(3):338-351.
PMID: 29431744
Deficits in Schwann cell-mediated remyelination impair functional restoration after nerve damage, contributing to peripheral neuropathies. The mechanisms mediating block of remyelination remain elusive. Here, through small-molecule screening focusing on epigenetic...
6.
Bai C, Sun S, Roholt A, Benson E, Edberg D, Medicetty S, et al.
Exp Neurol
. 2016 Jul;
283(Pt A):330-40.
PMID: 27384502
Used in combination with immunomodulatory therapies, remyelinating therapies are a viable therapeutic approach for treating individuals with multiple sclerosis. Studies of postmortem MS brains identified greater remyelination in demyelinated cerebral...
7.
Yamasaki R, Lu H, Butovsky O, Ohno N, Rietsch A, Cialic R, et al.
J Exp Med
. 2014 Jul;
211(8):1533-49.
PMID: 25002752
In the human disorder multiple sclerosis (MS) and in the model experimental autoimmune encephalomyelitis (EAE), macrophages predominate in demyelinated areas and their numbers correlate to tissue damage. Macrophages may be...
8.
Cooperrider J, Furmaga H, Plow E, Park H, Chen Z, Kidd G, et al.
J Neurosci
. 2014 Jul;
34(27):9040-50.
PMID: 24990924
Control over postinjury CNS plasticity is a major frontier of science that, if conquered, would open new avenues for treatment of neurological disorders. Here we investigate the functional, physiological, and...
9.
Nixon B, Ewen K, Krivanek K, Clulow J, Kidd G, Ecroyd H, et al.
Reproduction
. 2013 Dec;
147(3):265-77.
PMID: 24298048
The role of the avian epididymis in post-testicular development and capacitation was examined to assess whether avian spermatozoa undergo any processes similar to those characteristic of mammalian sperm development. We...
10.
Tait S, Oberst A, Quarato G, Milasta S, Haller M, Wang R, et al.
Cell Rep
. 2013 Nov;
5(4):878-85.
PMID: 24268776
Programmed necrosis (or necroptosis) is a form of cell death triggered by the activation of receptor interacting protein kinase-3 (RIPK3). Several reports have implicated mitochondria and mitochondrial reactive oxygen species...