Graham R Robertson
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Explore the profile of Graham R Robertson including associated specialties, affiliations and a list of published articles.
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26
Citations
806
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0
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Recent Articles
1.
Xie H, Heier C, Meng X, Bakiri L, Pototschnig I, Tang Z, et al.
Proc Natl Acad Sci U S A
. 2022 Feb;
119(9).
PMID: 35210363
Cancer-associated cachexia (CAC) is a hypermetabolic syndrome characterized by unintended weight loss due to the atrophy of adipose tissue and skeletal muscle. A phenotypic switch from white to beige adipocytes,...
2.
Wang J, Lewis J, Byrnes E, Wong G, Raymond W, Zhu K, et al.
Sci Rep
. 2020 Sep;
10(1):14499.
PMID: 32879333
Midkine (MDK), a heparin-binding growth factor cytokine, is involved in the pathogenesis of kidney diseases by augmenting leukocyte trafficking and activation. Animal models and small case control studies have implicated...
3.
Campbell V, Gately R, Krishnasamy R, Burg D, Robertson G, Gray N
Nephrol Dial Transplant
. 2020 Jun;
36(9):1577-1584.
PMID: 32542315
Chronic kidney disease (CKD) is a progressive multisystem condition with yet undefined mechanistic drivers and multiple implicated soluble factors. If identified, these factors could be targeted for therapeutic intervention for...
4.
Wang J, Zhou J, Robertson G, Lee V
Nutrients
. 2018 May;
10(5).
PMID: 29786640
Vascular calcification (VC) as a manifestation of perturbed mineral balance, is associated with aging, diabetes and kidney dysfunction, as well as poorer patient outcomes. Due to the current limited understanding...
5.
Tsoli M, Swarbrick M, Robertson G
Semin Cell Dev Biol
. 2015 Nov;
54:68-81.
PMID: 26529279
Although muscle wasting is the obvious manifestation of cancer cachexia that impacts on patient quality of life, the loss of lipid reserves and metabolic imbalance in adipose tissue also contribute...
6.
Kacevska M, Mahns A, Sharma R, Clarke S, Robertson G, Liddle C
Pharm Res
. 2013 Apr;
30(9):2270-8.
PMID: 23604979
Purpose: In many cancer patients, the malignancy causes reduced hepatic drug clearance leading to potentially serious complications from the use of anticancer drugs. The mechanisms underlying this phenomenon are poorly...
7.
Chellappa K, Robertson G, Sladek F
Biomark Med
. 2012 Jun;
6(3):297-300.
PMID: 22731903
No abstract available.
8.
Shum A, Mahendradatta T, Taylor R, Painter A, Moore M, Tsoli M, et al.
Aging (Albany NY)
. 2012 Feb;
4(2):133-43.
PMID: 22361433
Cancer cachexia is a highly debilitating paraneoplastic disease observed in more than 50% of patients with advanced cancers and directly contributes to 20% of cancer deaths. Loss of skeletal muscle...
9.
Chellappa K, Jankova L, Schnabl J, Pan S, Brelivet Y, Fung C, et al.
Proc Natl Acad Sci U S A
. 2012 Feb;
109(7):2302-7.
PMID: 22308320
Src tyrosine kinase has long been implicated in colon cancer but much remains to be learned about its substrates. The nuclear receptor hepatocyte nuclear factor 4α (HNF4α) has just recently...
10.
Fung D, Lo A, Jankova L, Clarke S, Molloy M, Robertson G, et al.
Methods Mol Biol
. 2011 Aug;
781:311-36.
PMID: 21877288
Molecular expression patterns have often been used for patient classification in oncology in an effort to improve prognostic prediction and treatment compatibility. This effort is, however, hampered by the highly...