Gillian R Douce
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Explore the profile of Gillian R Douce including associated specialties, affiliations and a list of published articles.
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21
Citations
577
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Recent Articles
1.
Wale K, OBoyle N, McHugh R, Serrano E, Mark D, Douce G, et al.
PLoS Pathog
. 2024 Oct;
20(10):e1012451.
PMID: 39405360
The ability of the attaching and effacing pathogens enterohaemorrhagic Escherichia coli (EHEC) and Citrobacter rodentium to overcome colonisation resistance is reliant on a type 3 secretion system used to intimately...
2.
Rimbi P, OBoyle N, Douce G, Pizza M, Rosini R, Roe A
J Appl Microbiol
. 2024 Mar;
135(4).
PMID: 38486355
Aims: The main objective of this study was to modify a recently reported multi-purpose artificial urine (MP-AU) for culture and gene expression studies of uropathogenic Escherichia coli (UPEC) strains. Methods...
3.
Ormsby M, Vaz F, Kirk J, Barwinska-Sendra A, Hallam J, Lanzoni-Mangutchi P, et al.
PLoS Pathog
. 2023 Jun;
19(6):e1011015.
PMID: 37384772
Clostridioides difficile is responsible for substantial morbidity and mortality in antibiotically-treated, hospitalised, elderly patients, in which toxin production correlates with diarrhoeal disease. While the function of these toxins has been...
4.
OBoyle N, Douce G, Farrell G, Rattray N, Schembri M, Roe A, et al.
Proc Natl Acad Sci U S A
. 2022 Dec;
120(1):e2212175120.
PMID: 36574699
The ability of bacterial pathogens to adapt to host niches is driven by the carriage and regulation of genes that benefit pathogenic lifestyles. Genes that encode virulence or fitness-enhancing factors...
5.
Lanzoni-Mangutchi P, Banerji O, Wilson J, Barwinska-Sendra A, Kirk J, Vaz F, et al.
Nat Commun
. 2022 Feb;
13(1):970.
PMID: 35217634
Many bacteria and archaea possess a two-dimensional protein array, or S-layer, that covers the cell surface and plays crucial roles in cell physiology. Here, we report the crystal structure of...
6.
Aubry A, Zou W, Vinogradov E, Williams D, Chen W, Harris G, et al.
Vaccines (Basel)
. 2020 Feb;
8(1).
PMID: 32046000
The BclA3 glycoprotein is a major component of the exosporangial layer of spores and in this study we demonstrate that this glycoprotein is a major spore surface associated antigen. Here,...
7.
Connolly J, Slater S, OBoyle N, Goldstone R, Crepin V, Ruano-Gallego D, et al.
Nat Commun
. 2018 Dec;
9(1):5148.
PMID: 30498235
The original version of this Article contained an error in the spelling of the author David Ruano-Gallego, which was incorrectly given as David R. Gallego. This has now been corrected...
8.
Connolly J, Slater S, OBoyle N, Goldstone R, Crepin V, Ruano-Gallego D, et al.
Nat Commun
. 2018 Oct;
9(1):4187.
PMID: 30305622
Niche-adaptation of a bacterial pathogen hinges on the ability to recognize the complexity of signals from the environment and integrate that information with the regulation of genes critical for infection....
9.
Kirk J, Gebhart D, Buckley A, Lok S, Scholl D, Douce G, et al.
Sci Transl Med
. 2017 Sep;
9(406).
PMID: 28878013
There is a medical need for antibacterial agents that do not damage the resident gut microbiota or promote the spread of antibiotic resistance. We recently described a prototypic precision bactericidal...
10.
McCaughey L, Ritchie N, Douce G, Evans T, Walker D
Sci Rep
. 2016 Jul;
6:30201.
PMID: 27444885
Protein antibiotics, known as bacteriocins, are widely produced by bacteria for intraspecies competition. The potency and targeted action of bacteriocins suggests that they could be developed into clinically useful antibiotics...