Andrew J Roe
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Explore the profile of Andrew J Roe including associated specialties, affiliations and a list of published articles.
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90
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1816
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Recent Articles
1.
Christopher J, Craig R, McHugh R, Roe A, Bauer R, Patton B, et al.
J Microsc
. 2025 Feb;
PMID: 39996362
We present the manufacture and characterisation of a 3D-printed, low-cost optical microscope using both a 3D-printed chassis and 3D-printed illumination and imaging optics. The required commercial components, consisting of a...
2.
Mark D, OBoyle N, Wale K, Tucker S, McHugh R, Roe A
Open Biol
. 2024 Nov;
14(11):240240.
PMID: 39591989
Gram-negative pathogens pose a significant threat due to their propensity for causing various infections, often coupled with formidable resistance to conventional antibiotic treatments. The development of antivirulence (AV) compounds emerges...
3.
Wale K, OBoyle N, McHugh R, Serrano E, Mark D, Douce G, et al.
PLoS Pathog
. 2024 Oct;
20(10):e1012451.
PMID: 39405360
The ability of the attaching and effacing pathogens enterohaemorrhagic Escherichia coli (EHEC) and Citrobacter rodentium to overcome colonisation resistance is reliant on a type 3 secretion system used to intimately...
4.
Tucker S, McHugh R, Roe A
Cell Signal
. 2024 Jun;
121:111253.
PMID: 38852937
Shiga toxin-producing Escherichia coli (STEC) are a group of enteric pathogens which carry phage-encoded Shiga toxins (Stx). STEC infections begin with severe abdominal pain and non-bloody diarrhoea, which can progress...
5.
Rimbi P, OBoyle N, Douce G, Pizza M, Rosini R, Roe A
J Appl Microbiol
. 2024 Mar;
135(4).
PMID: 38486355
Aims: The main objective of this study was to modify a recently reported multi-purpose artificial urine (MP-AU) for culture and gene expression studies of uropathogenic Escherichia coli (UPEC) strains. Methods...
6.
Addington E, Sandalli S, Roe A
Microbiology (Reading)
. 2024 Feb;
170(2).
PMID: 38314762
The biosynthetic machinery for the production of colibactin is encoded by 19 genes () within the pathogenicity island harboured by many of the B2-phylogroup. Colibactin is a potent genotoxic metabolite...
7.
Sirisaengtaksin N, ODonoghue E, Jabbari S, Roe A, Krachler A
mSphere
. 2023 Nov;
8(6):e0052023.
PMID: 37929984
Bacteria can package protein cargo into nanosized membrane blebs that are shed from the bacterial membrane and released into the environment. Here, we report that a type of pathogenic bacteria...
8.
Hallam J, Sandalli S, Floria I, Turner N, Tang-Fichaux M, Oswald E, et al.
Microb Cell
. 2023 Mar;
10(3):63-77.
PMID: 36908282
Some strains harbour the island, a 54 kb genomic island encoding the biosynthesis genes for a genotoxic compound named colibactin. In eukaryotic cells, colibactin can induce DNA damage, cell cycle...
9.
Loughlin S, Costello H, Roe A, Buckley C, Wilson S, Bailey M, et al.
Kidney360
. 2023 Feb;
4(2):226-240.
PMID: 36821614
No abstract available.
10.
OBoyle N, Douce G, Farrell G, Rattray N, Schembri M, Roe A, et al.
Proc Natl Acad Sci U S A
. 2022 Dec;
120(1):e2212175120.
PMID: 36574699
The ability of bacterial pathogens to adapt to host niches is driven by the carriage and regulation of genes that benefit pathogenic lifestyles. Genes that encode virulence or fitness-enhancing factors...