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Gert Van den Eynden

Explore the profile of Gert Van den Eynden including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 1793
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Recent Articles
1.
Fimereli D, Venet D, Rediti M, Boeckx B, Maetens M, Majjaj S, et al.
EBioMedicine . 2022 Jul; 82:104169. PMID: 35882101
Background: Late distant recurrence is a challenge for the treatment of invasive lobular carcinoma (ILC) of the breast. Despite in-depth characterisation of primary ILC, the molecular landscape of metastatic ILC...
2.
Gomez-Aleza C, Nguyen B, Yoldi G, Ciscar M, Barranco A, Hernandez-Jimenez E, et al.
Nat Commun . 2020 Dec; 11(1):6335. PMID: 33303745
Most breast cancers exhibit low immune infiltration and are unresponsive to immunotherapy. We hypothesized that inhibition of the receptor activator of nuclear factor-κB (RANK) signaling pathway may enhance immune activation....
3.
Richard F, Majjaj S, Venet D, Rothe F, Pingitore J, Boeckx B, et al.
Clin Cancer Res . 2020 Sep; 26(23):6254-6265. PMID: 32943456
Purpose: Invasive lobular carcinoma (ILC) represents the second most common histologic breast cancer subtype after invasive ductal carcinoma (IDC). While primary ILC has been extensively studied, metastatic ILC has been...
4.
Kos Z, Roblin E, Kim R, Michiels S, Gallas B, Chen W, et al.
NPJ Breast Cancer . 2020 May; 6:17. PMID: 32411819
Stromal tumor-infiltrating lymphocytes (sTILs) are important prognostic and predictive biomarkers in triple-negative (TNBC) and HER2-positive breast cancer. Incorporating sTILs into clinical practice necessitates reproducible assessment. Previously developed standardized scoring guidelines...
5.
Sonnenblick A, Salmon-Divon M, Salgado R, Dvash E, Ponde N, Zahavi T, et al.
Int J Cancer . 2020 Jan; 147(1):266-276. PMID: 31904863
We investigated the value of reactive stroma as a predictor for trastuzumab resistance in patients with early HER2-positive breast cancer receiving adjuvant therapy. The pathological reactive stroma and the mRNA...
6.
Garaud S, Buisseret L, Solinas C, Gu-Trantien C, De Wind A, Van den Eynden G, et al.
JCI Insight . 2019 Aug; 5. PMID: 31408436
Tumor-infiltrating B-cells (TIL-B) in breast cancer (BC) have previously been associated with improved clinical outcomes; however, their role(s) in tumor immunity is not currently well known. This study confirms and...
7.
Mignon S, Willard-Gallo K, Van den Eynden G, Salgado R, Decoster L, Marien K, et al.
Pathol Oncol Res . 2019 Jun; 26(2):1221-1228. PMID: 31228073
Tumor infiltrating lymphocytes (TIL), programmed death 1 (PD-1) and programmed death-ligand 1 (PD-L1) expression are important prognostic markers. This study aimed to investigate these markers in lung adenocarcinoma (ADC) biopsies...
8.
Desmedt C, Pingitore J, Rothe F, Marchio C, Clatot F, Rouas G, et al.
NPJ Breast Cancer . 2019 Mar; 5:9. PMID: 30820448
Invasive lobular breast cancer (ILC) represents the second most common histology of breast cancer after invasive ductal breast cancer (IDC), accounts for up to 15% of all invasive cases and...
9.
Solinas C, Marcoux D, Garaud S, Rodrigues Vitoria J, Van den Eynden G, De Wind A, et al.
Cancer Lett . 2019 Feb; 450:88-97. PMID: 30797818
This study investigated the prevalence of TIL subpopulations, TLS, PD-1 and PD-L1 in tumors from TNBC patients harboring wild-type or mutated BRCA1 or BRCA2 germline genes. This TNBC cohort included...
10.
Gruosso T, Gigoux M, Manem V, Bertos N, Zuo D, Perlitch I, et al.
J Clin Invest . 2019 Feb; 129(4):1785-1800. PMID: 30753167
Understanding the tumor immune microenvironment (TIME) promises to be key for optimal cancer therapy, especially in triple-negative breast cancer (TNBC). Integrating spatial resolution of immune cells with laser capture microdissection...