Gert J Meersma
Overview
Explore the profile of Gert J Meersma including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
67
Followers
0
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Recent Articles
1.
Caumanns J, Li S, Meersma G, Duiker E, van der Zee A, Wisman G, et al.
Sci Rep
. 2025 Feb;
15(1):4434.
PMID: 39910133
Interest in understanding the high chemoresistance and poor prognosis of advanced ovarian clear cell carcinoma (OCCC) is rising. Patient-derived xenografts (PDX) are widely used in vivo models because of their...
2.
Caumanns J, van Wijngaarden A, Kol A, Meersma G, Jalving M, Bernards R, et al.
Cancer Lett
. 2019 Jul;
461:102-111.
PMID: 31319139
Advanced stage ovarian clear cell carcinoma (OCCC) is poorly responsive to platinum-based chemotherapy and has an unfavorable prognosis. Previous studies revealed heterogeneous mutations in PI3K/AKT/mTOR and MAPK pathway nodules converging...
3.
Caumanns J, Berns K, Wisman G, Fehrmann R, Tomar T, Klip H, et al.
Clin Cancer Res
. 2018 Apr;
24(16):3928-3940.
PMID: 29685880
Advanced-stage ovarian clear cell carcinoma (OCCC) is unresponsive to conventional platinum-based chemotherapy. Frequent alterations in OCCC include deleterious mutations in the tumor suppressor and activating mutations in the PI3K subunit...
4.
Tan S, Hougardy B, Meersma G, Schaap B, de Vries E, van der Zee A, et al.
Mol Pharmacol
. 2012 Feb;
81(5):701-9.
PMID: 22328720
In cervical cancer, the p53 and retinoblastoma (pRb) tumor suppressor pathways are disrupted by the human papilloma virus (HPV) E6 and E7 oncoproteins, because E6 targets p53 and E7 targets...