Gerard Klein
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Explore the profile of Gerard Klein including associated specialties, affiliations and a list of published articles.
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20
Citations
304
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Recent Articles
1.
Habourdin C, Klein G, Araki T, Williams J, Aubry L
Cell Commun Signal
. 2013 Nov;
11:91.
PMID: 24267687
Background: Cell behaviour is tightly determined by sensing and integration of extracellular changes through membrane detectors such as receptors and transporters and activation of downstream signalling cascades. Arrestin proteins act...
2.
Aubry L, Klein G
Prog Mol Biol Transl Sci
. 2013 Jun;
118:21-56.
PMID: 23764049
Arrestin-clan proteins are folded alike, a feature responsible for their recent grouping in a single clan. In human, it includes the well-characterized visual and β-arrestins, the arrestin domain-containing proteins (ARRDCs),...
3.
Journet A, Klein G, Brugiere S, Vandenbrouck Y, Chapel A, Kieffer S, et al.
Proteomics
. 2011 Nov;
12(2):241-5.
PMID: 22120990
The cellular slime mold Dictyostelium discoideum is a soil-living eukaryote, which feeds on microorganisms engulfed by phagocytosis. Axenic laboratory strains have been produced that are able to use liquid growth...
4.
Guetta D, Langou K, Grunwald D, Klein G, Aubry L
PLoS One
. 2010 Dec;
5(12):e15249.
PMID: 21179207
Background: Visual and β-arrestins are scaffolding proteins involved in the regulation of receptor-dependent intracellular signaling and their trafficking. The arrestin superfamilly includes several arrestin domain-containing proteins and the structurally related...
5.
Aubry L, Guetta D, Klein G
Curr Genomics
. 2009 Oct;
10(2):133-42.
PMID: 19794886
Endocytosis of ligand-activated plasma membrane receptors has been shown to contribute to the regulation of their downstream signaling. beta-arrestins interact with the phosphorylated tail of activated receptors and act as...
6.
Giusti C, Luciani M, Klein G, Aubry L, Tresse E, Kosta A, et al.
Exp Cell Res
. 2008 Oct;
315(1):26-38.
PMID: 18951891
Dictyostelium atg1- mutant cells provide an experimentally and genetically favorable model to study necrotic cell death (NCD) with no interference from apoptosis or autophagy. In such cells subjected to starvation...
7.
Satre M, Mattei S, Aubry L, Gaudet P, Pelosi L, Brandolin G, et al.
Biochimie
. 2007 Apr;
89(9):1058-69.
PMID: 17442478
Proteins of the mitochondrial carrier family (MCF) mediate the transport of a large range of compounds, including metabolites and cofactors. They are localized mainly in the inner mitochondrial membrane, except...
8.
Aubry L, Klein G
Methods Mol Biol
. 2006 Sep;
346:171-85.
PMID: 16957290
In the following protocols, broken cells are the starting material of all downstream purifications of functional organelles or intact subcellular membranes. The choice of the breakage method has direct and...
9.
Mattei S, Klein G, Satre M, Aubry L
Eur J Cell Biol
. 2006 Jun;
85(9-10):925-36.
PMID: 16766083
Alix is a phylogenetically conserved protein that participates in mammals in programmed cell death in association with ALG-2, a penta-EF-hand calciprotein. It contains an N-terminal Bro1 domain, a coiled-coil region...
10.
Benghezal M, Fauvarque M, Tournebize R, Froquet R, Marchetti A, Bergeret E, et al.
Cell Microbiol
. 2005 Dec;
8(1):139-48.
PMID: 16367873
The amoeba Dictyostelium discoideum shares many traits with mammalian macrophages, in particular the ability to phagocytose and kill bacteria. In response, pathogenic bacteria use conserved mechanisms to fight amoebae and...