Nicolas Humbert
Overview
Explore the profile of Nicolas Humbert including associated specialties, affiliations and a list of published articles.
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Articles
45
Citations
415
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0
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Recent Articles
1.
Delaitre C, Boisbrun M, Acherar S, Dias A, Kleinclauss A, Achard M, et al.
J Med Chem
. 2024 Nov;
67(22):20275-20297.
PMID: 39526976
Angiotensin II (AngII) regulates cerebral circulation and binds with a similar affinity to AT and AT receptors. Biased AT agonists, such as TRV027, which are able to selectively activate β-arrestin...
2.
Berthome Y, Gerber J, Hanser F, Riche S, Humbert N, Valencia C, et al.
Bioconjug Chem
. 2024 Jul;
35(8):1182-1189.
PMID: 38982626
Fluorogenic dimers with polarity-sensitive folding are powerful probes for live-cell bioimaging. They switch on their fluorescence only after interacting with their targets, thus leading to a high signal-to-noise ratio in...
3.
Batisse C, Lapaillerie D, Humbert N, Real E, Zhu R, Mely Y, et al.
J Biol Chem
. 2024 May;
300(6):107374.
PMID: 38762180
The pre-integration steps of the HIV-1 viral cycle are some of the most valuable targets of recent therapeutic innovations. HIV-1 integrase (IN) displays multiple functions, thanks to its considerable conformational...
4.
Chery M, Berrissou C, Humbert N, Hummel G, Mely Y, Salinas-Giege T, et al.
Plant J
. 2023 Dec;
118(1):124-140.
PMID: 38113339
As in many other organisms, tRNA-derived RNAs (tDRs) exist in plants and likely have multiple functions. We previously showed that tDRs are present in Arabidopsis under normal growth conditions, and...
5.
Murate M, Yokoyama N, Tomishige N, Richert L, Humbert N, Pollet B, et al.
Cell Mol Life Sci
. 2023 May;
80(6):167.
PMID: 37249637
Monosialoganglioside GM3 is the simplest ganglioside involved in various cellular signaling. Cell surface distribution of GM3 is thought to be crucial for the function of GM3, but little is known...
6.
Taha N, Zgheib S, Sharma K, Humbert N, Boutant E, Didier P, et al.
Viruses
. 2022 Aug;
14(8).
PMID: 36016420
The Human Immunodeficiency Virus-1 (HIV-1) nucleocapsid protein (NC) as a mature protein or as a domain of the Gag precursor plays important roles in the early and late phases of...
7.
Grytsyk N, Cianfarani D, Cregut O, Richert L, Boudier C, Humbert N, et al.
Nucleic Acids Res
. 2021 Aug;
49(19):e111.
PMID: 34450653
Interconversions between nucleic acid structures play an important role in transcriptional and translational regulation and also in repair and recombination. These interconversions are frequently promoted by nucleic acid chaperone proteins....
8.
Jiang K, Humbert N, K K S, Rouzina I, Mely Y, Westerlund F
Nucleic Acids Res
. 2021 Apr;
49(8):4550-4563.
PMID: 33872352
The nucleocapsid (NC) protein plays key roles in Human Immunodeficiency Virus 1 (HIV-1) replication, notably by condensing and protecting the viral RNA genome and by chaperoning its reverse transcription into...
9.
Karnib H, Nadeem M, Humbert N, Sharma K, Grytsyk N, Tisne C, et al.
Nucleic Acids Res
. 2020 Aug;
48(16):9218-9234.
PMID: 32797159
The HIV-1 Gag protein playing a key role in HIV-1 viral assembly has recently been shown to interact through its nucleocapsid domain with the ribosomal protein L7 (RPL7) that acts...
10.
Ciaco S, Humbert N, Real E, Boudier C, Francesconi O, Roelens S, et al.
ACS Med Chem Lett
. 2020 May;
11(5):698-705.
PMID: 32435373
The HIV-1 nucleocapsid protein 7 (NC) is a potential target for effective antiretroviral therapy due to its central role in virus replication, mainly linked to nucleic acid (NA) chaperone activity,...