George M C Janssen
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Explore the profile of George M C Janssen including associated specialties, affiliations and a list of published articles.
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54
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1509
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Recent Articles
1.
de Jong M, Schaftenaar F, Depuydt M, Lozano Vigario F, Janssen G, Peeters J, et al.
Arterioscler Thromb Vasc Biol
. 2024 Mar;
44(6):1302-1314.
PMID: 38511327
Introduction: Viral infections have been associated with the progression of atherosclerosis and CD8 T-cells directed against common viruses, such as influenza, Epstein-Barr virus, and cytomegalovirus, have been detected inside human...
2.
van den Bulk J, Verdegaal E, van der Ploeg M, Visser M, Nunes J, de Ru A, et al.
Clin Cancer Res
. 2023 Aug;
29(20):4278-4288.
PMID: 37540567
Purpose: The availability of (neo)antigens and the infiltration of tumors by (neo)antigen-specific T cells are crucial factors in cancer immunotherapy. In this study, we aimed to investigate the targetability of...
3.
Cabukusta B, Berlin I, van Elsland D, Forkink I, Spits M, de Jong A, et al.
Cell Rep
. 2023 Jul;
42(7):112849.
PMID: 37440407
No abstract available.
4.
van de Kooij B, de Vries E, Rooswinkel R, Janssen G, Kok F, Van Veelen P, et al.
Sci Rep
. 2023 Apr;
13(1):5333.
PMID: 37005459
The majority of proteins in mammalian cells are modified by covalent attachment of an acetyl-group to the N-terminus (Nt-acetylation). Paradoxically, Nt-acetylation has been suggested to inhibit as well as to...
5.
Hos B, Tondini E, Camps M, Rademaker W, van den Bulk J, Ruano D, et al.
Cell Rep
. 2022 Nov;
41(8):111680.
PMID: 36417866
No abstract available.
6.
van der Pan K, Kassem S, Khatri I, de Ru A, Janssen G, Tjokrodirijo R, et al.
Front Med (Lausanne)
. 2022 Oct;
9:997305.
PMID: 36237552
Mass spectrometry (MS)-based proteomics profiling has undoubtedly increased the knowledge about cellular processes and functions. However, its applicability for paucicellular sample analyses is currently limited. Although new approaches have been...
7.
Hos B, Tondini E, Camps M, Rademaker W, van den Bulk J, Ruano D, et al.
Cell Rep
. 2022 Oct;
41(2):111485.
PMID: 36223747
We report an approach to identify tumor-specific CD4 T cell neo-epitopes of both mouse and human cancer cells by analysis of major histocompatibility complex (MHC) class II-eluted natural peptides. MHC...
8.
Ruibal P, Franken K, van Meijgaarden K, van Wolfswinkel M, Derksen I, Scheeren F, et al.
J Immunol
. 2022 Sep;
209(8):1555-1565.
PMID: 36096642
Tuberculosis (TB) remains one of the deadliest infectious diseases worldwide, posing great social and economic burden to affected countries. Novel vaccine approaches are needed to increase protective immunity against the...
9.
Ali M, Giannakopoulou E, Li Y, Lehander M, Virding Culleton S, Yang W, et al.
Nat Biotechnol
. 2021 Dec;
40(4):488-498.
PMID: 34873326
Unlike chimeric antigen receptors, T-cell receptors (TCRs) can recognize intracellular targets presented on human leukocyte antigen (HLA) molecules. Here we demonstrate that T cells expressing TCRs specific for peptides from...
10.
Stavast C, van Zuijen I, Karkoulia E, Ozcelik A, van Hoven-Beijen A, Leon L, et al.
Leukemia
. 2021 Nov;
36(3):687-700.
PMID: 34741119
MIR139 is a tumor suppressor and is commonly silenced in acute myeloid leukemia (AML). However, the tumor-suppressing activities of miR-139 and molecular mechanisms of MIR139-silencing remain largely unknown. Here, we...