Tom W J Huizinga
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Explore the profile of Tom W J Huizinga including associated specialties, affiliations and a list of published articles.
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496
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23300
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Recent Articles
1.
Fukui S, Michitsuji T, Endo Y, Nishino A, Furukawa K, Morimoto S, et al.
RMD Open
. 2025 Jan;
11(1).
PMID: 39863304
Objectives: To evaluate the potential of clinical factors, ultrasound findings, serum autoantibodies, and serum cytokine and chemokine profiles as predictors of clinical outcomes in rheumatoid arthritis (RA). Patients And Methods:...
2.
Stork E, Kalaidopoulou Nteak S, van Rijswijck D, Damen J, Scherer H, Toes R, et al.
Mol Cell Proteomics
. 2025 Jan;
24(2):100900.
PMID: 39746544
Rheumatoid arthritis (RA) is characterized by synovial hyperplasia and cartilage/bone destruction. RA affects the synovial joints, the synovial lining, and the permeability of the synovium. As the latter is of...
3.
Major T, Takei R, Matsuo H, Leask M, Sumpter N, Topless R, et al.
Nat Genet
. 2024 Nov;
56(11):2577.
PMID: 39501129
No abstract available.
4.
Derksen V, Martinsson K, van Mourik A, Wagenaar C, Toes R, Walrabenstein W, et al.
Arthritis Rheumatol
. 2024 Oct;
77(3):272-282.
PMID: 39420623
Objective: Anti-citrullinated protein antibodies (ACPA) have been detected in sputum and saliva, indicating that anti-modified protein antibodies (AMPA) can be produced at mucosal sites in patients with rheumatoid arthritis (RA)....
5.
Major T, Takei R, Matsuo H, Leask M, Sumpter N, Topless R, et al.
Nat Genet
. 2024 Oct;
56(11):2392-2406.
PMID: 39406924
Gout is a chronic disease that is caused by an innate immune response to deposited monosodium urate crystals in the setting of hyperuricemia. Here, we provide insights into the molecular...
6.
Neppelenbroek S, Blomberg N, Kampstra A, van der Hem J, Huizinga T, Toes R, et al.
J Autoimmun
. 2024 Sep;
149:103320.
PMID: 39342827
Background: Autoimmune diseases (AIDs) are frequently hallmarked by the presence of autoreactive B cell responses which are involved in disease pathogenesis. However, the dynamics of such responses and their relation...
7.
van Oostveen W, Huizinga T, Fehres C
Immunol Rev
. 2024 Sep;
328(1):265-282.
PMID: 39248128
Systemic sclerosis (SSc) is a severe autoimmune disease characterized by vasculopathy, fibrosis, and dysregulated immunity, with hallmark autoantibodies targeting nuclear antigens such as centromere protein (ACA) and topoisomerase I (ATA)....
8.
van der Meulen S, Monahan R, Gelderman K, van Kooten C, Teng Y, Huizinga T, et al.
Eur J Immunol
. 2024 Aug;
54(11):e2450998.
PMID: 39165045
Systemic lupus erythematosus (SLE) is marked by excessive complement activation, contributing to tissue damage. Complement activation can be detected in many organs including the skin, kidney, and brain. The involvement...
9.
Acetylated bacterial proteins as potent antigens inducing an anti-modified protein antibody response
Volkov M, Kampstra A, van Schie K, van Mourik A, Kwekkeboom J, de Ru A, et al.
RMD Open
. 2024 Jul;
10(3).
PMID: 39038910
Objective: Gut-residing bacteria, such as , can acetylate their proteome under conditions of amine starvation. It is postulated that the (gut) microbiome is involved in the breach of immune tolerance...
10.
van der Pol J, Allaart C, Huizinga T, Bergstra S
RMD Open
. 2024 Jun;
10(2).
PMID: 38906542
No abstract available.