George H Rothblat
Overview
Explore the profile of George H Rothblat including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
73
Citations
5642
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Boone L, Lagor W, de la Llera Moya M, Niesen M, Rothblat G, Ness G
Atherosclerosis
. 2011 May;
218(1):77-82.
PMID: 21605865
Objective: The goal of this study was to examine the effects of thyroid hormone status on the ability of serum to accept cellular cholesterol. Methods And Results: Sera from hypophysectomized...
12.
Khera A, Cuchel M, de la Llera-Moya M, Rodrigues A, Burke M, Jafri K, et al.
N Engl J Med
. 2011 Jan;
364(2):127-35.
PMID: 21226578
Background: High-density lipoprotein (HDL) may provide cardiovascular protection by promoting reverse cholesterol transport from macrophages. We hypothesized that the capacity of HDL to accept cholesterol from macrophages would serve as...
13.
Influence of apolipoprotein A-I domain structure on macrophage reverse cholesterol transport in mice
Alexander E, Vedhachalam C, Sankaranarayanan S, de la Llera-Moya M, Rothblat G, Rader D, et al.
Arterioscler Thromb Vasc Biol
. 2010 Nov;
31(2):320-7.
PMID: 21071688
Objective: The goal of this study was to determine the influence of apolipoprotein A-I (apoA-I) tertiary structure domain properties on the antiatherogenic properties of the protein. Two chimeric hybrids with...
14.
Sankaranarayanan S, de la Llera-Moya M, Drazul-Schrader D, Asztalos B, Weibel G, Rothblat G
J Lipid Res
. 2010 Aug;
51(11):3243-9.
PMID: 20713652
Net flux of cholesterol represents the difference between efflux and influx and can result in net cell-cholesterol accumulation, net cell-cholesterol depletion, or no change in cellular cholesterol content. We measured...
15.
Vedhachalam C, Chetty P, Nickel M, Dhanasekaran P, Lund-Katz S, Rothblat G, et al.
J Biol Chem
. 2010 Aug;
285(42):31965-73.
PMID: 20679346
The principal protein of high density lipoprotein (HDL), apolipoprotein (apo) A-I, in the lipid-free state contains two tertiary structure domains comprising an N-terminal helix bundle and a less organized C-terminal...
16.
Brown R, Lagor W, Sankaranaravanan S, Yasuda T, Quertermous T, Rothblat G, et al.
Circ Res
. 2010 Jun;
107(3):357-64.
PMID: 20558822
Rationale: Hepatic lipase (HL) and endothelial lipase (EL) are extracellular lipases that both hydrolyze triglycerides and phospholipids and display potentially overlapping or complementary roles in lipoprotein metabolism. Objective: We sought...
17.
Rothblat G, Phillips M
Curr Opin Lipidol
. 2010 May;
21(3):229-38.
PMID: 20480549
Purpose Of Review: HDL is a cardioprotective lipoprotein, at least in part, because of its ability to mediate reverse cholesterol transport (RCT). It is becoming increasingly clear that the antiatherogenic...
18.
Zhang Y, McGillicuddy F, Hinkle C, ONeill S, Glick J, Rothblat G, et al.
Circulation
. 2010 Mar;
121(11):1347-55.
PMID: 20212278
Background: Adipose harbors a large depot of free cholesterol. However, a role for adipose in cholesterol lipidation of high-density lipoprotein (HDL) in vivo is not established. We present the first...
19.
de la Llera-Moya M, Drazul-Schrader D, Asztalos B, Cuchel M, Rader D, Rothblat G
Arterioscler Thromb Vasc Biol
. 2010 Jan;
30(4):796-801.
PMID: 20075420
Objective: We measured efflux from macrophages to apolipoprotein B-depleted serum from 263 specimens and found instances in which serum having similar high-density lipoprotein cholesterol (HDL-C) differed in their efflux capacity....
20.
Cuchel M, Lund-Katz S, de la Llera-Moya M, Millar J, Chang D, Fuki I, et al.
Arterioscler Thromb Vasc Biol
. 2009 Dec;
30(3):526-32.
PMID: 20018934
Objective: Reconstituted high-density lipoprotein (rHDL) is of interest as a potential novel therapy for atherosclerosis because of its ability to promote free cholesterol (FC) mobilization after intravenous administration. We performed...