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George E Griffin

Explore the profile of George E Griffin including associated specialties, affiliations and a list of published articles. Areas
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Articles 47
Citations 1829
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Recent Articles
1.
Li M, Zhang D, Li C, Zheng Z, Fu M, Ni F, et al.
Front Microbiol . 2020 Mar; 11:242. PMID: 32210929
Zika virus (ZIKV) infections can cause microcephaly and neurological disorders. However, the early infection events of ZIKV in neural cells remain to be characterized. Here, by using a combination of...
2.
Li C, Guan X, Du T, Jin W, Wu B, Liu Y, et al.
J Gen Virol . 2015 Apr; 96(8):2381-2393. PMID: 25854553
CCR5 serves as an essential coreceptor for human immunodeficiency virus type 1 (HIV-1) entry, and individuals with a CCR5(Δ32) variant appear to be healthy, making CCR5 an attractive target for...
3.
Looi L, Ganten D, McGrath P, Gross M, Griffin G
Lancet . 2015 Mar; 385(9972):943-4. PMID: 25743174
No abstract available.
4.
Liu Y, Luo S, He S, Zhang M, Wang P, Li C, et al.
Virology . 2014 Dec; 475:96-109. PMID: 25462350
Tetherin has been defined as a restriction factor of HIV-1 and several other enveloped viruses. However, the significance of tetherin in viral infection remains to be further addressed. Here, we...
5.
Batman P, Kapembwa M, Belmonte L, Tudor G, Kotler D, Potten C, et al.
J Clin Pathol . 2013 Jul; 67(1):14-8. PMID: 23881223
Objective: To analyse the structural and kinetic response of small intestinal crypt epithelial cells including stem cells to highly active antiretroviral therapy (HAART). Design: Crypt size and proliferative activity of...
6.
Hu K, Luo S, Tong L, Huang X, Jin W, Huang W, et al.
J Immunol . 2013 Jul; 191(4):1935-47. PMID: 23858028
Induction of broad and potent neutralizing Abs at the mucosal portals of entry remains a primary goal for most vaccines against mucosally acquired viral infections. Selection of appropriate adjuvants capable...
7.
Du T, Hu K, Yang J, Jin J, Li C, Stieh D, et al.
Antimicrob Agents Chemother . 2012 Jun; 56(9):4640-9. PMID: 22687513
Early stages of mucosal infection are potential targets for HIV-1 prevention. CD4 is the primary receptor in HIV-1 infection whereas DC-SIGN likely plays an important role in HIV-1 dissemination, particularly...
8.
Huang W, Hu K, Luo S, Zhang M, Li C, Jin W, et al.
J Immunol . 2012 May; 188(12):6247-57. PMID: 22586042
Recruitment of CD4(+) T cells to infection areas after HSV-2 infection may be one of the mechanisms that account for increased HIV-1 sexual transmission. Lymphocytes recruited by chemokine CXCL9 are...
9.
Huang X, Jin W, Hu K, Luo S, Du T, Griffin G, et al.
Virology . 2011 Dec; 423(1):97-106. PMID: 22192629
Glycosylation plays important roles in gp120 structure and HIV-1 immune evasion. In the current study, we introduced deglycosylations into the 24 N-linked glycosylation sites of a R5 env MWS2 cloned...
10.
Huang X, Jin W, Griffin G, Shattock R, Hu Q
J Gen Virol . 2011 Jul; 92(Pt 10):2367-2373. PMID: 21715597
High-mannose N-linked glycans recognized by carbohydrate-binding agents (CBAs) are potential targets for topical microbicides. To better understand the mechanisms by which CBAs inhibit human immunodeficiency virus (HIV)-1 infection at the...