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Diana L Wallace

Explore the profile of Diana L Wallace including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Wallace D, Masters J, de Lara C, Henson S, Worth A, Zhang Y, et al.
Immunology . 2010 Aug; 132(1):27-38. PMID: 20738423
The immune response to human cytomegalovirus (HCMV) infection is characterized by the accumulation of HCMV-specific CD8(+) T cells, particularly in the elderly; such expansions may impair immune responses to other...
2.
Asquith B, Zhang Y, Mosley A, de Lara C, Wallace D, Worth A, et al.
Proc Natl Acad Sci U S A . 2007 May; 104(19):8035-40. PMID: 17483473
Human T-lymphotropic virus type 1 (HTLV-1) is a persistent CD4+ T-lymphotropic retrovirus. Most HTLV-1-infected individuals remain asymptomatic, but a proportion develop adult T cell leukemia or inflammatory disease. It is...
3.
Zhang Y, Wallace D, de Lara C, Ghattas H, Asquith B, Worth A, et al.
Immunology . 2007 Mar; 121(2):258-65. PMID: 17346281
Human natural killer (NK) cells form a circulating population in a state of dynamic homeostasis. We investigated NK cell homeostasis by labelling dividing cells in vivo using deuterium-enriched glucose in...
4.
Ghattas H, Wallace D, Solon J, Henson S, Zhang Y, Ngom P, et al.
Am J Clin Nutr . 2007 Feb; 85(2):480-7. PMID: 17284747
Background: Nutritional status is highly dependent on season in countries such as The Gambia. In a rural Gambian setting, individuals born during periods of seasonal nutritional deprivation ("hungry seasons") are...
5.
Wallace D, Berard M, Soares M, Oldham J, Cook J, Akbar A, et al.
Immunology . 2006 Sep; 119(2):243-53. PMID: 17005004
Interleukin (IL)-7 and IL-15 are cytokines implicated in homeostatic control of the peripheral CD8 T-cell pool. We compared the effects of IL-7 and IL-15 on survival and proliferation of purified...
6.
Ghattas H, Darboe B, Wallace D, Griffin G, Prentice A, Macallan D
Trans R Soc Trop Med Hyg . 2005 Jun; 99(9):675-85. PMID: 15985275
Studies involving in-vivo labelling of lymphocyte DNA with 6,6-2H2-glucose to track T-cell turnover have contributed to understanding lymphocyte homeostasis in health and disease. Applying such studies in tropical settings (where...
7.
Macallan D, Wallace D, Zhang Y, Ghattas H, Asquith B, de Lara C, et al.
Blood . 2005 Jan; 105(9):3633-40. PMID: 15644412
Information about the kinetic behavior and lifespan of lymphocytes is crucial to understanding the mechanisms that regulate processes such as immunologic memory. We have used in vivo labeling of dividing...
8.
Wallace D, Zhang Y, Ghattas H, Worth A, Irvine A, Bennett A, et al.
J Immunol . 2004 Jul; 173(3):1787-94. PMID: 15265909
The age-associated decline in immunocompetence is paralleled by changes in the proportions of PBL subpopulations. In turn, the size and composition of the peripheral lymphocyte pool is determined by input...
9.
Macallan D, Wallace D, Irvine A, Asquith B, Worth A, Ghattas H, et al.
Eur J Immunol . 2003 Sep; 33(10):2655-65. PMID: 14515249
During acute infectious mononucleosis (AIM), large clones of Epstein-Barr virus-specific T lymphocytes are produced. To investigate the dynamics of clonal expansion, we measured cell proliferation during AIM using deuterated glucose...
10.
Macallan D, Asquith B, Irvine A, Wallace D, Worth A, Ghattas H, et al.
Eur J Immunol . 2003 Jul; 33(8):2316-26. PMID: 12884307
The ability to measure, describe and interpret T cell kinetics is pivotal in understanding normal lymphocyte homeostasis and diseases that affect T cell numbers. Following in vivo labeling of dividing...