Geetha Rao
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Explore the profile of Geetha Rao including associated specialties, affiliations and a list of published articles.
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37
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1254
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Recent Articles
1.
Rao G, Mack C, Nguyen T, Wong N, Payne K, Worley L, et al.
J Allergy Clin Immunol
. 2024 Dec;
PMID: 39622295
Background: CD4 T cells play essential roles in adaptive immunity. Distinct CD4 T-cell subsets-T1, T2, T17, T22, T follicular helper, and regulatory T cells-have been identified, and their contributions to...
2.
Ogishi M, Kitaoka K, Good-Jacobson K, Rinchai D, Zhang B, Wang J, et al.
Immunity
. 2024 Nov;
57(12):2790-2807.e15.
PMID: 39603236
T follicular helper (Tfh) cells abundantly express the immunoreceptor programmed cell death protein 1 (PD-1), and the impact of PD-1 deficiency on antibody (Ab)-mediated immunity in mice is associated with...
3.
Huynh A, Gray P, Sullivan A, Mackie J, Guerin A, Rao G, et al.
J Clin Immunol
. 2024 Sep;
45(1):11.
PMID: 39297999
No abstract available.
4.
Huynh A, Gray P, Sullivan A, Mackie J, Guerin A, Rao G, et al.
J Clin Immunol
. 2024 Aug;
44(8):170.
PMID: 39098944
Advanced genomic technologies such as whole exome or whole genome sequencing have improved diagnoses and disease outcomes for individuals with genetic diseases. Yet, variants of unknown significance (VUS) require rigorous...
5.
Guerin A, Moncada-Velez M, Jackson K, Ogishi M, Rosain J, Mancini M, et al.
J Exp Med
. 2024 Apr;
221(5).
PMID: 38557723
CD4+ T cells are vital for host defense and immune regulation. However, the fundamental role of CD4 itself remains enigmatic. We report seven patients aged 5-61 years from five families...
6.
Martin E, Winter S, Garcin C, Tanita K, Hoshino A, Lenoir C, et al.
Nature
. 2024 Mar;
628(8008):620-629.
PMID: 38509369
Epstein-Barr virus (EBV) infection can engender severe B cell lymphoproliferative diseases. The primary infection is often asymptomatic or causes infectious mononucleosis (IM), a self-limiting lymphoproliferative disorder. Selective vulnerability to EBV...
7.
Masle-Farquhar E, Jackson K, Peters T, Al-Eryani G, Singh M, Payne K, et al.
Immunity
. 2022 Nov;
55(12):2386-2404.e8.
PMID: 36446385
The association between cancer and autoimmune disease is unexplained, exemplified by T cell large granular lymphocytic leukemia (T-LGL) where gain-of-function (GOF) somatic STAT3 mutations correlate with co-existing autoimmunity. To investigate...
8.
Pelham S, Caldirola M, Avery D, Mackie J, Rao G, Gothe F, et al.
J Allergy Clin Immunol
. 2022 Apr;
150(4):931-946.
PMID: 35469842
Background: Lymphocyte differentiation is regulated by coordinated actions of cytokines and signaling pathways. IL-21 activates STAT1, STAT3, and STAT5 and is fundamental for the differentiation of human B cells into...
9.
Levy R, Langlais D, Beziat V, Rapaport F, Rao G, Lazarov T, et al.
J Clin Invest
. 2021 Oct;
131(17).
PMID: 34623332
We studied a child with severe viral, bacterial, fungal, and parasitic diseases, who was homozygous for a loss-of-function mutation of REL, encoding c-Rel, which is selectively expressed in lymphoid and...
10.
Beziat V, Rapaport F, Hu J, Titeux M, Bonnet des Claustres M, Bourgey M, et al.
Cell
. 2021 Jul;
184(14):3812-3828.e30.
PMID: 34214472
We study a patient with the human papilloma virus (HPV)-2-driven "tree-man" phenotype and two relatives with unusually severe HPV4-driven warts. The giant horns form an HPV-2-driven multifocal benign epithelial tumor...