Galit Shahaf
Overview
Explore the profile of Galit Shahaf including associated specialties, affiliations and a list of published articles.
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20
Citations
453
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Recent Articles
1.
Ozeri E, Rider P, Rigbi S, Shahaf G, Nita I, Sekler I, et al.
Cell Immunol
. 2021 Jan;
361:104281.
PMID: 33453508
Dendritic cells (DCs) mature upon an inflammatory trigger. However, an inflammatory trigger can lead to a semi-mature phenotype, allowing DCs to evoke tolerance and expedite the resolution of inflammation. This...
2.
Baranovski B, Ozeri E, Shahaf G, Ochayon D, Schuster R, Bahar N, et al.
J Pharmacol Exp Ther
. 2016 Nov;
359(3):482-490.
PMID: 27821710
Life-long weekly infusions of human α1-antitrypsin (hAAT) are currently administered as augmentation therapy for patients with genetic AAT deficiency (AATD). Several recent clinical trials attempt to extend hAAT therapy to...
3.
Kaner Z, Ochayon D, Shahaf G, Baranovski B, Bahar N, Mizrahi M, et al.
J Infect Dis
. 2014 Nov;
211(9):1489-98.
PMID: 25389308
Background: Severe bacterial infection can cause sepsis, multiple organ dysfunction syndrome (MODS), and death. Human α1-antitrypsin (hAAT) is an antiinflammatory, immune-modulating, and tissue-protective circulating serine-protease inhibitor, with levels that increase...
4.
Abecassis A, Schuster R, Shahaf G, Ozeri E, Green R, Ochayon D, et al.
Cell Mol Immunol
. 2014 Jul;
11(4):377-86.
PMID: 25000533
Although islet transplantation for individuals with type 1 diabetes has been shown to yield superior blood glucose control, it remains inadequate for long-term control. This is partly due to islet...
5.
Yaniv Salem S, Shahaf G, Sheiner E, Levinson J, Baron J, Madar T, et al.
J Matern Fetal Neonatal Med
. 2014 May;
28(5):500-3.
PMID: 24834800
Objective: To examine possible correlation between α1-antitrypsin (AAT) levels and activity in patients with and without obesity, after excluding complications such as gestational diabetes mellitus (GDM), during pregnancy. Study Design:...
6.
Ochayon D, Mizrahi M, Shahaf G, Baranovski B, Lewis E
Front Immunol
. 2013 Nov;
4:320.
PMID: 24191154
The extracellular form of the abundant heat-shock protein, gp96, is involved in human autoimmune pathologies. In patients with type 1 diabetes, circulating gp96 is found to be elevated, and is...
7.
Jonigk D, Al-Omari M, Maegel L, Muller M, Izykowski N, Hong J, et al.
Proc Natl Acad Sci U S A
. 2013 Aug;
110(37):15007-12.
PMID: 23975926
The rationale of α1-antitrypsin (AAT) augmentation therapy to treat progressive emphysema in AAT-deficient patients is based on inhibition of neutrophil elastase; however, the benefit of this treatment remains unclear. Here...
8.
Mizrahi M, Cal P, Rosenthal M, Ochayon D, Shahaf G, Kaner Z, et al.
Immunology
. 2013 Jul;
140(3):362-73.
PMID: 23829472
B-lymphocyte activities are associated with allograft rejection. Interleukin-10 (IL-10) -expressing B cells, however, exhibit regulatory attributes. Human α1-antitrypsin (hAAT), a clinically available anti-inflammatory circulating glycoprotein that rises during acute-phase responses,...
9.
Ashkenazi E, Baranovski B, Shahaf G, Lewis E
PLoS One
. 2013 May;
8(5):e63625.
PMID: 23717456
Clinical pancreatic islet transplantation is under evaluation for the treatment of autoimmune diabetes, yet several limitations preclude widespread use. For example, there is a critical shortage of human pancreas donors....
10.
Madar T, Shahaf G, Sheiner E, Brazg J, Levinson J, Yaniv Salem S, et al.
J Matern Fetal Neonatal Med
. 2013 May;
26(18):1782-7.
PMID: 23650930
Objective: Alpha-1 antitrypsin (AAT), a circulating anti-inflammatory molecule, rises four- to sixfold during acute phase responses and during pregnancy. AAT deficiency is linked with various pregnancy complications. The aim of...