David E Ochayon
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Explore the profile of David E Ochayon including associated specialties, affiliations and a list of published articles.
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Citations
227
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Recent Articles
1.
DeVore S, Schuetz M, Alvey L, Lujan H, Ochayon D, Williams L, et al.
Cell Rep
. 2024 Aug;
43(8):114589.
PMID: 39110589
Caspase recruitment domain family member 14 (CARD14) and its variants are associated with both atopic dermatitis (AD) and psoriasis, but their mechanistic impact on skin barrier homeostasis is largely unknown....
2.
Ochayon D, DeVore S, Chang W, Krishnamurthy D, Seelamneni H, Grashel B, et al.
Sci Immunol
. 2024 Feb;
9(92):eadd3085.
PMID: 38335270
Atopic dermatitis (AD) is a chronic inflammatory skin disease that often precedes the development of food allergy, asthma, and allergic rhinitis. The prevailing paradigm holds that a reduced frequency and...
3.
Ochayon D, DeVore S, Chang W, Krishnamurthy D, Seelamneni H, Grashel B, et al.
medRxiv
. 2023 Jun;
PMID: 37333102
Atopic dermatitis (AD) is a chronic inflammatory skin disease that often precedes the development of food allergy, asthma, and allergic rhinitis. The prevailing paradigm holds that a reduced frequency and...
4.
Tang Y, Xu Q, Hu L, Yan X, Feng X, Yokota A, et al.
Cancer Discov
. 2021 Jul;
11(12):3142-3157.
PMID: 34193438
Significance: Our study identifies novel targets in enhancing antitumor immunity and sensitizing immune checkpoint inhibition, which provides a rationale for developing new immunotherapies against cancers. It also offers mechanistic insights...
5.
Ochayon D, Waggoner S
Front Immunol
. 2021 Apr;
12:645850.
PMID: 33815404
Cytokines are soluble and membrane-bound factors that dictate immune responses. Dogmatically, cytokines are divided into families that promote type 1 cell-mediated immune responses (e.g., IL-12) or type 2 humoral responses...
6.
Reighard S, Krishnamurthy D, Cevik H, Ochayon D, Ali A, Seelamneni H, et al.
Cytotherapy
. 2020 Oct;
23(1):37-45.
PMID: 33092988
Background Aims: Certain therapies (e.g., daclizumab) that promote expansion of natural killer (NK) cells are associated with clinical amelioration of disease in the context of multiple sclerosis and associated mouse...
7.
Lior Y, Jasevitch M, Ochayon D, Zaretsky M, Lewis E, Aharoni A
Cell Immunol
. 2020 Jul;
355:104135.
PMID: 32703529
Primarily known as an elastase inhibitor, human alpha1-antitrypsin also exerts anti-inflammatory and immunomodulatory effects, both in vitro and in vivo. While the anti-protease mechanism of alpha1-antitrypsin is attributed to a...
8.
Rajaram S, Canaday L, Ochayon D, Rangel K, Ali A, Gyurova I, et al.
Immunity
. 2020 May;
52(6):887-889.
PMID: 32405233
No abstract available.
9.
Ochayon D, Ali A, Alarcon P, Krishnamurthy D, Kottyan L, Borchers M, et al.
J Leukoc Biol
. 2020 Feb;
107(4):663-671.
PMID: 32017227
This study tests the hypothesis that activation of MAPK by physiologically relevant concentrations of IL-33 contributes to enhanced cytokine expression by IL-12 stimulated human NK cells. While IL-33 canonically triggers...
10.
Gyurova I, Schlums H, Sucharew H, Ambroggio L, Ochayon D, Win H, et al.
Front Immunol
. 2019 Dec;
10:2728.
PMID: 31824507
Individuals lacking functional natural killer (NK) cells suffer severe, recurrent infections with cytomegalovirus (CMV), highlighting the critical role of NK cells in antiviral defense. Therefore, ongoing attempts to develop an...