Gabriele Hintzen
Overview
Explore the profile of Gabriele Hintzen including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
1043
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0
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Recent Articles
1.
El-Khoueiry A, Saavedra O, Thomas J, Livings C, Garralda E, Hintzen G, et al.
Clin Cancer Res
. 2025 Jan;
PMID: 39846810
Purpose: Innate immune cell-based therapies have shown promising antitumor activity against solid and hematologic malignancies. AFM24, a bispecific innate cell engager, binds CD16A on natural killer (NK) cells/macrophages and EGFR...
2.
Richards S, Gubser Keller C, Kreutzer R, Greiner G, Ley S, Doelemeyer A, et al.
Int Wound J
. 2023 Dec;
21(4):e14447.
PMID: 38149752
A limited understanding of the pathology underlying chronic wounds has hindered the development of effective diagnostic markers and pharmaceutical interventions. This study aimed to elucidate the molecular composition of various...
3.
Hintzen G, Dulat H, Rajkovic E
Front Oncol
. 2022 Oct;
12:892212.
PMID: 36185288
The epidermal growth factor receptor (EGFR) is a key player in the normal tissue physiology and the pathology of cancer. Therapeutic approaches have now been developed to target oncogenic genetic...
4.
Ruffner H, Sprunger J, Charlat O, Leighton-Davies J, Grosshans B, Salathe A, et al.
PLoS One
. 2012 Jul;
7(7):e40976.
PMID: 22815884
The Wnt/β-catenin signaling pathbway controls many important biological processes. R-Spondin (RSPO) proteins are a family of secreted molecules that strongly potentiate Wnt/β-catenin signaling, however, the molecular mechanism of RSPO action...
5.
Kocks J, Davalos-Misslitz A, Hintzen G, Ohl L, Forster R
J Exp Med
. 2007 Mar;
204(4):723-34.
PMID: 17371929
Presence and extent of bronchus-associated lymphoid tissue (BALT) is subject to considerable variations between species and is only occasionally observed in lungs of mice. Here we demonstrate that mice deficient...
6.
Hintzen G, Ohl L, Del Rio M, Rodriguez-Barbosa J, Pabst O, Kocks J, et al.
J Immunol
. 2006 Nov;
177(10):7346-54.
PMID: 17082654
Allergic airway diseases such as asthma are caused by a failure of the immune system to induce tolerance against environmental Ags. The underlying molecular and cellular mechanisms that initiate tolerance...
7.
Worbs T, Bode U, Yan S, Hoffmann M, Hintzen G, Bernhardt G, et al.
J Exp Med
. 2006 Mar;
203(3):519-27.
PMID: 16533884
Oral tolerance induction is a key feature of intestinal immunity, generating systemic nonresponsiveness to ingested antigens. In this study, we report that orally applied soluble antigens are exclusively recognized in...
8.
Ohl L, Mohaupt M, Czeloth N, Hintzen G, Kiafard Z, Zwirner J, et al.
Immunity
. 2004 Aug;
21(2):279-88.
PMID: 15308107
The CC chemokine receptor CCR7 has been identified as a key regulator of homeostatic B and T cell trafficking to secondary lymphoid organs. Data presented here demonstrate that CCR7 is...
9.
Misslitz A, Pabst O, Hintzen G, Ohl L, Kremmer E, Petrie H, et al.
J Exp Med
. 2004 Aug;
200(4):481-91.
PMID: 15302903
T cell differentiation in the adult thymus depends on sequential interactions between lymphoid progenitors and stromal cells found in distinct regions of the cortex and medulla. Therefore, migration of T...