Gabriel J Starrett
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Explore the profile of Gabriel J Starrett including associated specialties, affiliations and a list of published articles.
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46
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2164
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Recent Articles
21.
Tisza M, Pastrana D, Welch N, Stewart B, Peretti A, Starrett G, et al.
Elife
. 2020 Feb;
9.
PMID: 32014111
Although millions of distinct virus species likely exist, only approximately 9000 are catalogued in GenBank's RefSeq database. We selectively enriched for the genomes of circular DNA viruses in over 70...
22.
Ondov B, Starrett G, Sappington A, Kostic A, Koren S, Buck C, et al.
Genome Biol
. 2019 Nov;
20(1):232.
PMID: 31690338
The MinHash algorithm has proven effective for rapidly estimating the resemblance of two genomes or metagenomes. However, this method cannot reliably estimate the containment of a genome within a metagenome....
23.
Serebrenik A, Starrett G, Leenen S, Jarvis M, Shaban N, Salamango D, et al.
Proc Natl Acad Sci U S A
. 2019 Oct;
116(44):22158-22163.
PMID: 31611371
Human cells express up to 9 active DNA cytosine deaminases with functions in adaptive and innate immunity. Many cancers manifest an APOBEC mutation signature and APOBEC3B (A3B) is likely the...
24.
Starrett G, Buck C
Curr Opin Virol
. 2019 Jul;
39:8-15.
PMID: 31336246
In 2014, the International Agency for Research on Cancer judged Merkel cell polyomavirus (MCPyV) to be a probable human carcinogen. BK polyomavirus (BKPyV, a distant cousin of MCPyV) was ruled...
25.
Starrett G, Serebrenik A, Roelofs P, McCann J, Verhalen B, Jarvis M, et al.
mBio
. 2019 Feb;
10(1).
PMID: 30723127
APOBEC3B is a single-stranded DNA cytosine deaminase with beneficial innate antiviral functions. However, misregulated APOBEC3B can also be detrimental by inflicting APOBEC signature C-to-T and C-to-G mutations in genomic DNA...
26.
Pastrana D, Peretti A, Welch N, Borgogna C, Olivero C, Badolato R, et al.
mSphere
. 2018 Dec;
3(6).
PMID: 30541782
Several immunodeficiencies are associated with high susceptibility to persistent and progressive human papillomavirus (HPV) infection leading to a wide range of cutaneous and mucosal lesions. However, the HPV types most...
27.
Ebrahimi D, Richards C, Carpenter M, Wang J, Ikeda T, Becker J, et al.
Nat Commun
. 2018 Oct;
9(1):4137.
PMID: 30297863
Human APOBEC3H (A3H) is a single-stranded DNA cytosine deaminase that inhibits HIV-1. Seven haplotypes (I-VII) and four splice variants (SV154/182/183/200) with differing antiviral activities and geographic distributions have been described,...
28.
Peretti A, Geoghegan E, Pastrana D, Smola S, Feld P, Sauter M, et al.
Cell Host Microbe
. 2018 May;
23(5):628-635.e7.
PMID: 29746834
BK polyomavirus (BKV) frequently causes nephropathy (BKVN) in kidney transplant recipients (KTRs). BKV has also been implicated in the etiology of bladder and kidney cancers. We characterized BKV variants from...
29.
Molan A, Hanson H, Chweya C, Anderson B, Starrett G, Richards C, et al.
Virology
. 2017 Aug;
511:74-81.
PMID: 28841445
The APOBEC3 DNA cytosine deaminase family comprises a fundamental arm of the innate immune response and is best known for retrovirus restriction. Several APOBEC3 enzymes restrict HIV-1 and related retroviruses...
30.
Starrett G, Marcelus C, Cantalupo P, Katz J, Cheng J, Akagi K, et al.
mBio
. 2017 Jan;
8(1).
PMID: 28049147
Importance: A variety of mutagenic processes that shape the evolution of tumors are critical determinants of disease outcome. Here, we sequenced the entire genome of virus-positive and virus-negative primary Merkel...