Gregory R Wojtkiewicz
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Explore the profile of Gregory R Wojtkiewicz including associated specialties, affiliations and a list of published articles.
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71
Citations
2904
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Recent Articles
1.
Wang C, Jalali Motlagh N, Wojtkiewicz G, Yang H, Kim H, Chen J
Theranostics
. 2025 Jan;
15(3):1094-1109.
PMID: 39776805
The mannose receptor (CD206, expressed by the gene ) is a surface marker overexpressed by anti-inflammatory and pro-tumoral macrophages. As such, CD206 macrophages play key roles in the immune response...
2.
Wang H, Miranda M, Marutani E, Lichtenegger P, Wojtkiewicz G, Ichinose F, et al.
J Clin Invest
. 2024 Dec;
134(23).
PMID: 39621311
No abstract available.
3.
Quintana J, Kang M, Hu H, Ng T, Wojtkiewicz G, Scott E, et al.
ACS Cent Sci
. 2024 Jul;
10(7):1371-1382.
PMID: 39071065
Radiotherapy is commonly used to treat cancer, and localized energy deposited by radiotherapy has the potential to chemically uncage prodrugs; however, it has been challenging to demonstrate prodrug activation that...
4.
Ferrer C, Cho H, Boon R, Bernasocchi T, Wong L, Cetinbas M, et al.
Nat Cell Biol
. 2024 Jun;
26(6):975-990.
PMID: 38862786
Identifying the adaptive mechanisms of metastatic cancer cells remains an elusive question in the treatment of metastatic disease, particularly in pancreatic cancer (pancreatic adenocarcinoma, PDA). A loss-of-function shRNA targeted screen...
5.
Grune J, Bajpai G, Ocak P, Kaufmann E, Mentkowski K, Pabel S, et al.
Circulation
. 2024 Mar;
150(1):49-61.
PMID: 38506045
Background: Viral infections can cause acute respiratory distress syndrome (ARDS), systemic inflammation, and secondary cardiovascular complications. Lung macrophage subsets change during ARDS, but the role of heart macrophages in cardiac...
6.
Fan Y, Leape C, Hugard S, McCanne M, Thomson A, Wojtkiewicz G, et al.
BMC Musculoskelet Disord
. 2023 Nov;
24(1):854.
PMID: 37907937
Background: Rodent models are commonly employed to validate preclinical disease models through the evaluation of postoperative behavior and allodynia. Our study investigates the dynamic interplay between pain and functional recovery...
7.
Hulsmans M, Schloss M, Lee I, Bapat A, Iwamoto Y, Vinegoni C, et al.
Science
. 2023 Jul;
381(6654):231-239.
PMID: 37440641
Atrial fibrillation disrupts contraction of the atria, leading to stroke and heart failure. We deciphered how immune and stromal cells contribute to atrial fibrillation. Single-cell transcriptomes from human atria documented...
8.
Zeller M, Wang C, Keliher E, Wojtkiewicz G, Aguirre A, Maresca K, et al.
Int J Mol Sci
. 2023 Mar;
24(6).
PMID: 36982778
Myeloperoxidase (MPO) is a highly oxidative, pro-inflammatory enzyme involved in post-myocardial infarction (MI) injury and is a potential therapeutic target. While multiple MPO inhibitors have been developed, the lack of...
9.
Altalhi W, Wu T, Wojtkiewicz G, Jeffs S, Miki K, Ott H
J Thorac Cardiovasc Surg
. 2023 Mar;
166(1):e23-e37.
PMID: 36933786
Objectives: Pulmonary emphysema is characterized by the destruction of alveolar units and reduced gas exchange capacity. In the present study, we aimed to deliver induced pluripotent stem cell-derived endothelial cells...
10.
Grune J, Lewis A, Yamazoe M, Hulsmans M, Rohde D, Xiao L, et al.
Nat Cardiovasc Res
. 2022 Aug;
1(7):649-664.
PMID: 36034743
Sudden cardiac death, arising from abnormal electrical conduction, occurs frequently in patients with coronary heart disease. Myocardial ischemia simultaneously induces arrhythmia and massive myocardial leukocyte changes. In this study, we...