Frederik Sundermann
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Explore the profile of Frederik Sundermann including associated specialties, affiliations and a list of published articles.
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11
Citations
323
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Recent Articles
1.
Hrynchak M, Rierola M, Golovyashkina N, Penazzi L, Pump W, David B, et al.
Front Synaptic Neurosci
. 2020 May;
12:16.
PMID: 32390822
Alzheimer's disease is regarded as a synaptopathy with a long presymptomatic phase. Soluble, oligomeric amyloid-β (Aβ) is thought to play a causative role in this disease, which eventually leads to...
2.
Gauthier-Kemper A, Suarez Alonso M, Sundermann F, Niewidok B, Fernandez M, Bakota L, et al.
J Biol Chem
. 2018 Apr;
293(21):8065-8076.
PMID: 29636414
During neuronal development, the microtubule-associated protein tau becomes enriched in the axon, where it remains concentrated in the healthy brain. In tauopathies such as Alzheimer's disease, tau redistributes from the...
3.
Penazzi L, Lorengel J, Sundermann F, Golovyashkina N, Marre S, Mathis C, et al.
Neuropharmacology
. 2016 Nov;
113(Pt A):434-444.
PMID: 27773645
DMSO has a widespread use as a vehicle for water-insoluble therapeutic drug candidates but may also exert disease-relevant pharmacological effects by itself. However, its influence on the CNS has hardly...
4.
Niewidok B, Igaev M, Sundermann F, Janning D, Bakota L, Brandt R
Mol Biol Cell
. 2016 Sep;
27(22):3537-3549.
PMID: 27582388
A current challenge of cell biology is to investigate molecular interactions in subcellular compartments of living cells to overcome the artificial character of in vitro studies. To dissect the interaction...
5.
Sundermann F, Fernandez M, Morgan R
BMC Genomics
. 2016 Apr;
17:264.
PMID: 27030133
Background: The microtubule associated protein Tau (MAPT) promotes assembly and interaction of microtubules with the cytoskeleton, impinging on axonal transport and synaptic plasticity. Its neuronal expression and intrinsic disorder implicate...
6.
Igaev M, Janning D, Sundermann F, Niewidok B, Brandt R, Junge W
Biophys J
. 2014 Dec;
107(11):2567-78.
PMID: 25468336
Fluorescence decay after photoactivation (FDAP) and fluorescence recovery after photobleaching (FRAP) are well established approaches for studying the interaction of the microtubule (MT)-associated protein tau with MTs in neuronal cells....
7.
Janning D, Igaev M, Sundermann F, Bruhmann J, Beutel O, Heinisch J, et al.
Mol Biol Cell
. 2014 Aug;
25(22):3541-51.
PMID: 25165145
The microtubule-associated phosphoprotein tau regulates microtubule dynamics and is involved in neurodegenerative diseases collectively called tauopathies. It is generally believed that the vast majority of tau molecules decorate axonal microtubules,...
8.
Gauthier-Kemper A, Igaev M, Sundermann F, Janning D, Bruhmann J, Moschner K, et al.
Mol Biol Cell
. 2014 Aug;
25(21):3284-99.
PMID: 25165142
Phosphorylation and lipidation provide posttranslational mechanisms that contribute to the distribution of cytosolic proteins in growing nerve cells. The growth-associated protein GAP43 is susceptible to both phosphorylation and S-palmitoylation and...
9.
Moschner K, Sundermann F, Meyer H, Pereira da Graca A, Appel N, Paululat A, et al.
J Biol Chem
. 2014 Apr;
289(24):16814-25.
PMID: 24755223
The neuronal microtubule-associated protein Tau is expressed in different variants, and changes in Tau isoform composition occur during development and disease. Here, we investigate a potential role of the multivalent...
10.
Sundermann F, Golovyashkina N, Tackenberg C, Brandt R, Bakota L
Methods Mol Biol
. 2012 Feb;
846:277-93.
PMID: 22367819
Dendritic spines act as sites of excitatory neuronal input in many types of neurons. Spine shape correlates with the strength and maturity of synaptic contacts. Thus, evaluation of spine morphology...