Dennis Janning
Overview
Explore the profile of Dennis Janning including associated specialties, affiliations and a list of published articles.
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7
Citations
254
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Recent Articles
1.
Conze C, Rierola M, Trushina N, Peters M, Janning D, Holzer M, et al.
Mol Psychiatry
. 2022 Apr;
27(7):3010-3023.
PMID: 35393558
The microtubule-associated protein tau plays a central role in tauopathies such as Alzheimer's disease (AD). The exact molecular mechanisms underlying tau toxicity are unclear, but aging is irrefutably the biggest...
2.
Niewidok B, Igaev M, Sundermann F, Janning D, Bakota L, Brandt R
Mol Biol Cell
. 2016 Sep;
27(22):3537-3549.
PMID: 27582388
A current challenge of cell biology is to investigate molecular interactions in subcellular compartments of living cells to overcome the artificial character of in vitro studies. To dissect the interaction...
3.
Barlag B, Beutel O, Janning D, Czarniak F, Richter C, Kommnick C, et al.
Sci Rep
. 2016 Aug;
6:31601.
PMID: 27534893
The investigation of the subcellular localization, dynamics and interaction of proteins and protein complexes in prokaryotes is complicated by the small size of the cells. Super-resolution microscopy (SRM) comprise various...
4.
Wilmes S, Beutel O, Li Z, Francois-Newton V, Richter C, Janning D, et al.
J Cell Biol
. 2015 May;
209(4):579-93.
PMID: 26008745
Type I interferons (IFNs) activate differential cellular responses through a shared cell surface receptor composed of the two subunits, IFNAR1 and IFNAR2. We propose here a mechanistic model for how...
5.
Igaev M, Janning D, Sundermann F, Niewidok B, Brandt R, Junge W
Biophys J
. 2014 Dec;
107(11):2567-78.
PMID: 25468336
Fluorescence decay after photoactivation (FDAP) and fluorescence recovery after photobleaching (FRAP) are well established approaches for studying the interaction of the microtubule (MT)-associated protein tau with MTs in neuronal cells....
6.
Janning D, Igaev M, Sundermann F, Bruhmann J, Beutel O, Heinisch J, et al.
Mol Biol Cell
. 2014 Aug;
25(22):3541-51.
PMID: 25165145
The microtubule-associated phosphoprotein tau regulates microtubule dynamics and is involved in neurodegenerative diseases collectively called tauopathies. It is generally believed that the vast majority of tau molecules decorate axonal microtubules,...
7.
Gauthier-Kemper A, Igaev M, Sundermann F, Janning D, Bruhmann J, Moschner K, et al.
Mol Biol Cell
. 2014 Aug;
25(21):3284-99.
PMID: 25165142
Phosphorylation and lipidation provide posttranslational mechanisms that contribute to the distribution of cytosolic proteins in growing nerve cells. The growth-associated protein GAP43 is susceptible to both phosphorylation and S-palmitoylation and...