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Frederic Biemar

Explore the profile of Frederic Biemar including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 506
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Recent Articles
1.
Biemar F, Foti M
Cancer Biol Med . 2013 Dec; 10(4):183-6. PMID: 24349827
The last ten years have seen remarkable progress in cancer research. However, despite significant breakthroughs in the understanding, prevention, and treatment of cancer, the disease continues to affect millions of...
2.
Balciuniene J, Nagelberg D, Walsh K, Camerota D, Georlette D, Biemar F, et al.
BMC Genomics . 2013 Sep; 14:619. PMID: 24034702
Background: External development and optical transparency of embryos make zebrafish exceptionally suitable for in vivo insertional mutagenesis using fluorescent proteins to visualize expression patterns of mutated genes. Recently developed Gene...
3.
Verbruggen V, Ek O, Georlette D, Delporte F, Von Berg V, Detry N, et al.
J Biol Chem . 2010 Feb; 285(18):13863-73. PMID: 20177065
Pax6 is a well conserved transcription factor that contains two DNA-binding domains, a paired domain and a homeodomain, and plays a key role in the development of eye, brain, and...
4.
Delporte F, Pasque V, Devos N, Manfroid I, Voz M, Motte P, et al.
BMC Dev Biol . 2008 May; 8:53. PMID: 18485195
Background: PAX6 is a transcription factor playing a crucial role in the development of the eye and in the differentiation of the pancreatic endocrine cells as well as of enteroendocrine...
5.
Manak J, Dike S, Sementchenko V, Kapranov P, Biemar F, Long J, et al.
Nat Genet . 2006 Sep; 38(10):1151-8. PMID: 16951679
Many animal and plant genomes are transcribed much more extensively than current annotations predict. However, the biological function of these unannotated transcribed regions is largely unknown. Approximately 7% and 23%...
6.
Biemar F, Nix D, Piel J, Peterson B, Ronshaugen M, Sementchenko V, et al.
Proc Natl Acad Sci U S A . 2006 Aug; 103(34):12763-8. PMID: 16908844
Dorsal-ventral (DV) patterning of the Drosophila embryo is initiated by Dorsal, a sequence-specific transcription factor distributed in a broad nuclear gradient in the precellular embryo. Previous studies have identified as...
7.
Ellertsdottir E, Ganz J, Durr K, Loges N, Biemar F, Seifert F, et al.
Dev Dyn . 2006 Apr; 235(7):1794-808. PMID: 16628609
While there is a good conceptual framework of dorsoventral and anterioposterior axes formation in most vertebrate groups, understanding of left-right axis initiation is fragmentary. Diverse mechanisms have been implied to...
8.
Ronshaugen M, Biemar F, Piel J, Levine M, Lai E
Genes Dev . 2005 Dec; 19(24):2947-52. PMID: 16357215
The Drosophila Bithorax Complex encodes three well-characterized homeodomain proteins that direct segment identity, as well as several noncoding RNAs of unknown function. Here, we analyze the iab-4 locus, which produces...
9.
Biemar F, Zinzen R, Ronshaugen M, Sementchenko V, Manak J, Levine M
Proc Natl Acad Sci U S A . 2005 Oct; 102(44):15907-11. PMID: 16249329
MicroRNAs (miRNAs) regulate posttranscriptional gene activity by binding to specific sequences in the 3' UTRs of target mRNAs. A number of metazoan miRNAs have been shown to exhibit tissue-specific patterns...
10.
Mavropoulos A, Devos N, Biemar F, Zecchin E, Argenton F, Edlund H, et al.
Dev Biol . 2005 Aug; 285(1):211-23. PMID: 16055112
Pancreas development relies on a network of transcription factors belonging mainly to the Homeodomain and basic Helix-Loop-Helix families. We show in this study that, in zebrafish, sox4, a member of...