Isabelle Manfroid
Overview
Explore the profile of Isabelle Manfroid including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
507
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Recent Articles
1.
Massoz L, Bergemann D, Lavergne A, Reynders C, Desiront C, Goossens C, et al.
Elife
. 2024 Oct;
12.
PMID: 39383064
Stimulation of pancreatic beta cell regeneration could be a therapeutic lead to treat diabetes. Unlike humans, the zebrafish can efficiently regenerate beta cells, notably from ductal pancreatic progenitors. To gain...
2.
Streiff C, He B, Morvan L, Zhang H, Delrez N, Fourrier M, et al.
Viruses
. 2023 Mar;
15(3).
PMID: 36992477
The zebrafish () represents an increasingly important model organism in virology. We evaluated its utility in the study of economically important viruses from the genus (anguillid herpesvirus 1, cyprinid herpesvirus...
3.
Reuter A, Stern D, Bernard A, Goossens C, Lavergne A, Flasse L, et al.
PLoS Genet
. 2022 Mar;
18(3):e1010109.
PMID: 35286299
ARP/ASCL transcription factors are key determinants of cell fate specification in a wide variety of tissues, coordinating the acquisition of generic cell fates and of specific subtype identities. How these...
4.
Carril Pardo C, Massoz L, Dupont M, Bergemann D, Bourdouxhe J, Lavergne A, et al.
Elife
. 2022 Jan;
11.
PMID: 35060900
Restoring damaged β-cells in diabetic patients by harnessing the plasticity of other pancreatic cells raises the questions of the efficiency of the process and of the functionality of the new...
5.
Lopez-Perez A, Balwierz P, Lenhard B, Muller F, Wardle F, Manfroid I, et al.
Sci Rep
. 2021 Nov;
11(1):22717.
PMID: 34811400
Retinoic acid (RA) is a key signal for the specification of the pancreas. Still, the gene regulatory cascade triggered by RA in the endoderm remains poorly characterized. In this study,...
6.
Moortgat S, Manfroid I, Pendeville H, Freeman S, Bourdouxhe J, Benoit V, et al.
Hum Mutat
. 2021 May;
42(7):827-834.
PMID: 33942450
Mental deficiency, epilepsy, hypogonadism, microcephaly, and obesity syndrome is a severe X-linked syndrome caused by pathogenic variants in EIF2S3. The gene encodes the γ subunit of the eukaryotic translation initiation...
7.
Massoz L, Dupont M, Manfroid I
Biomedicines
. 2021 Jan;
9(1).
PMID: 33445518
Regeneration is defined as the ability to regrow an organ or a tissue destroyed by degeneration or injury. Many human degenerative diseases and pathologies, currently incurable, could be cured if...
8.
Lavergne A, Tarifeno-Saldivia E, Pirson J, Reuter A, Flasse L, Manfroid I, et al.
BMC Biol
. 2020 Sep;
18(1):109.
PMID: 32867764
Background: Endocrine cells of the zebrafish digestive system play an important role in regulating metabolism and include pancreatic endocrine cells (PECs) clustered in the islets of Langerhans and the enteroendocrine...
9.
Bergemann D, Massoz L, Bourdouxhe J, Carril Pardo C, Voz M, Peers B, et al.
Wound Repair Regen
. 2018 Apr;
26(2):238-244.
PMID: 29663654
The zebrafish is a popular animal model with well-known regenerative capabilities. To study regeneration in this fish, the nitroreductase/metronidazole-mediated system is widely used for targeted ablation of various cell types....
10.
Demarez C, Gerard C, Cordi S, Poncy A, Achouri Y, Dauguet N, et al.
Hepatology
. 2017 Aug;
67(1):313-327.
PMID: 28833283
Conclusion: Our results identify miR-337-3p as a regulator of liver development and highlight how tight quantitative control of hepatic cell differentiation is exerted through specific gene regulatory network motifs. (Hepatology...