Joseph A Martial
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Explore the profile of Joseph A Martial including associated specialties, affiliations and a list of published articles.
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42
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1318
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Recent Articles
1.
Figueroa M, Sleutel M, Vandevenne M, Parvizi G, Attout S, Jacquin O, et al.
J Struct Biol
. 2016 May;
195(1):19-30.
PMID: 27181418
Despite impressive successes in protein design, designing a well-folded protein of more 100 amino acids de novo remains a formidable challenge. Exploiting the promising biophysical features of the artificial protein...
2.
Herkenne S, Paques C, Nivelles O, Lion M, Bajou K, Pollenus T, et al.
Sci Signal
. 2015 Nov;
8(403):ra117.
PMID: 26577922
In endothelial cells, binding of vascular endothelial growth factor (VEGF) to the receptor VEGFR2 activates multiple signaling pathways that trigger processes such as proliferation, survival, and migration that are necessary...
3.
Bajou K, Herkenne S, Thijssen V, DAmico S, Nguyen N, Bouche A, et al.
Nat Med
. 2015 May;
21(5):537.
PMID: 25951534
No abstract available.
4.
Bovy N, Blomme B, Freres P, Dederen S, Nivelles O, Lion M, et al.
Oncotarget
. 2015 Apr;
6(12):10253-66.
PMID: 25860935
The interaction between tumor cells and their microenvironment is an essential aspect of tumor development. Therefore, understanding how this microenvironment communicates with tumor cells is crucial for the development of...
5.
Bajou K, Herkenne S, Thijssen V, DAmico S, Nguyen N, Bouche A, et al.
Nat Med
. 2014 Jun;
20(7):741-7.
PMID: 24929950
The N-terminal fragment of prolactin (16K PRL) inhibits tumor growth by impairing angiogenesis, but the underlying mechanisms are unknown. Here, we found that 16K PRL binds the fibrinolytic inhibitor plasminogen...
6.
Larbuisson A, Dalcq J, Martial J, Muller M
Differentiation
. 2013 Nov;
86(4-5):192-206.
PMID: 24176552
Cranial cartilage derives mainly from cranial neural crest cells and its formation requires fibroblast growth factor (Fgf) signaling for early differentiation and survival of developing chondrocytes as well as patterning...
7.
Figueroa M, Oliveira N, Lejeune A, Kaufmann K, Dorr B, Matagne A, et al.
PLoS One
. 2013 Aug;
8(8):e71858.
PMID: 23977165
The computational protein design protocol Rosetta has been applied successfully to a wide variety of protein engineering problems. Here the aim was to test its ability to design de novo...
8.
Tabruyn S, Hansen S, Ojeda-Fernandez M, Bovy N, Zarrabeitia R, Recio-Poveda L, et al.
Angiogenesis
. 2013 Jun;
16(4):877-87.
PMID: 23800974
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disorder characterized by arteriovenous malformations and hemorrhages. This vascular disease results mainly from mutations in 2 genes involved in the TGF-β pathway...
9.
Halkein J, Tabruyn S, Ricke-Hoch M, Haghikia A, Nguyen N, Scherr M, et al.
J Clin Invest
. 2013 Apr;
123(5):2143-54.
PMID: 23619365
Peripartum cardiomyopathy (PPCM) is a life-threatening pregnancy-associated cardiomyopathy in previously healthy women. Although PPCM is driven in part by the 16-kDa N-terminal prolactin fragment (16K PRL), the underlying molecular mechanisms...
10.
Dalcq J, Pasque V, Ghaye A, Larbuisson A, Motte P, Martial J, et al.
PLoS One
. 2012 Dec;
7(11):e50140.
PMID: 23209659
The cartilaginous elements forming the pharyngeal arches of the zebrafish derive from cranial neural crest cells. Their proper differentiation and patterning are regulated by reciprocal interactions between neural crest cells...