Frank Bennett
Overview
Explore the profile of Frank Bennett including associated specialties, affiliations and a list of published articles.
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44
Citations
624
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Recent Articles
1.
Zhang Y, Sun C, Guo L, Zhao K, Bennett F, Lam Y, et al.
J Org Chem
. 2025 Jan;
90(2):1175-1179.
PMID: 39745425
A novel, highly diastereoselective, and metal-free synthesis of multisubstituted piperidines via an S1 approach is reported in this study. The method allows for the preparation of highly functionalized compounds with...
2.
Bennett F, Huang Y, Dong S, Jiang J, Hunter D, Zhao Z, et al.
Bioorg Med Chem Lett
. 2024 Oct;
114:129989.
PMID: 39396683
The design, syntheses and antibacterial evaluation of sulfone analogues of previously disclosed metallo-β-lactamase inhibitors (MBLis) are described. The novel derivatives were overall more effective in gram-negative bacterial cell-based assays when...
3.
Dong S, Zhao Z, Tang H, Li G, Pan J, Gu X, et al.
J Med Chem
. 2024 Feb;
67(5):3400-3418.
PMID: 38387069
The use of β-lactam (BL) and β-lactamase inhibitor combination to overcome BL antibiotic resistance has been validated through clinically approved drug products. However, unmet medical needs still exist for the...
4.
Benatar M, Ostrow L, Lewcock J, Bennett F, Shefner J, Bowser R, et al.
Ann Neurol
. 2023 Dec;
95(2):211-216.
PMID: 38110839
Objective: To explore whether the utility of neurofilament light chain (NfL), as a biomarker to aid amyotrophic lateral sclerosis (ALS) therapy development, would be enhanced by obtaining formal qualification from...
5.
Rothstein J, Baskerville V, Rapuri S, Mehlhop E, Jafar-Nejad P, Rigo F, et al.
Acta Neuropathol
. 2023 Nov;
147(1):1.
PMID: 38019311
The GC repeat expansion in the C9orf72 gene is the most common genetic cause of Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Many studies suggest that dipeptide repeat proteins produced from...
6.
Ait Benichou S, Jauvin D, De Serres-Berard T, Bennett F, Rigo F, Gourdon G, et al.
Hum Gene Ther
. 2022 Jul;
33(15-16):810-820.
PMID: 35794764
Myotonic dystrophy type 1 (DM1) is a neuromuscular disorder that affects many organs. It is caused by the expansion of a cytosine-thymine-guanine triplet repeat in the 3' untranslated region of...
7.
Coyne A, Baskerville V, Zaepfel B, Dickson D, Rigo F, Bennett F, et al.
Sci Transl Med
. 2021 Jul;
13(604).
PMID: 34321318
Alterations in the components [nucleoporins (Nups)] and function of the nuclear pore complex (NPC) have been implicated as contributors to the pathogenesis of genetic forms of neurodegeneration including amyotrophic lateral...
8.
OConner-Von S, Bennett F
J Gerontol Nurs
. 2020 Nov;
46(12):23-29.
PMID: 33232494
Long-term care (LTC) nurses are a critical nexus for patient communication and vital to advance care planning due to their professional role and breadth of patient relationships. The current study's...
9.
Reilly S, Bennett F, Fier P, Ren S, Strotman N
Chemistry
. 2020 Feb;
26(19):4251-4255.
PMID: 32003092
A late-stage O labeling approach of sulfonamides that employs the corresponding unlabeled molecule as the starting material was developed. Upon deamination of the sulfonamide, a sulfinate intermediate was isotopically enriched...
10.
Bennett F, OConner-Von S
J Hosp Palliat Nurs
. 2019 Nov;
22(1):40-48.
PMID: 31764395
Effective communication between clinicians and seriously ill patients and their families about a patient's goals of care is essential to patient-centered, goal-concordant, end-of-life care. Effective goals-of-care communication between clinicians and...