Francois Vigneault
Overview
Explore the profile of Francois Vigneault including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
2061
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0
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Recent Articles
1.
Gordin M, Philip H, Zilberberg A, Gidoni M, Margalit R, Clouser C, et al.
PLoS Comput Biol
. 2021 Jan;
17(1):e1008486.
PMID: 33465095
The partial success of tumor immunotherapy induced by checkpoint blockade, which is not antigen-specific, suggests that the immune system of some patients contain antigen receptors able to specifically identify tumor...
2.
Trivedi N, Weisel F, Smita S, Joachim S, Kader M, Radhakrishnan A, et al.
Immunity
. 2019 Nov;
51(6):1088-1101.e5.
PMID: 31732168
The B cell response to Ehrlichia muris is dominated by plasmablasts (PBs), with few-if any-germinal centers (GCs), yet it generates protective immunoglobulin M (IgM) memory B cells (MBCs) that express...
3.
Carter J, Preall J, Grigaityte K, Goldfless S, Jeffery E, Briggs A, et al.
Front Immunol
. 2019 Aug;
10:1516.
PMID: 31417541
Although structural studies of individual T cell receptors (TCRs) have revealed important roles for both the α and β chain in directing MHC and antigen recognition, repertoire-level immunogenomic analyses have...
4.
Gidoni M, Snir O, Peres A, Polak P, Lindeman I, Mikocziova I, et al.
Nat Commun
. 2019 Feb;
10(1):628.
PMID: 30733445
Analysis of antibody repertoires by high-throughput sequencing is of major importance in understanding adaptive immune responses. Our knowledge of variations in the genomic loci encoding immunoglobulin genes is incomplete, resulting...
5.
Eliyahu S, Sharabi O, Elmedvi S, Timor R, Davidovich A, Vigneault F, et al.
Front Immunol
. 2019 Jan;
9:3004.
PMID: 30622532
Hepatitis C virus (HCV) is a major public health concern, with over 70 million people infected worldwide, who are at risk for developing life-threatening liver disease. No vaccine is available,...
6.
Gupta N, Adams K, Briggs A, Timberlake S, Vigneault F, Kleinstein S
J Immunol
. 2017 Feb;
198(6):2489-2499.
PMID: 28179494
Adaptive immunity is driven by the expansion, somatic hypermutation, and selection of B cell clones. Each clone is the progeny of a single B cell responding to Ag, with diversified...
7.
Laustsen A, Engmark M, Clouser C, Timberlake S, Vigneault F, Gutierrez J, et al.
PeerJ
. 2017 Feb;
5:e2924.
PMID: 28149694
Snakebite envenomings represent a neglected public health issue in many parts of the rural tropical world. Animal-derived antivenoms have existed for more than a hundred years and are effective in...
8.
Vander Heiden J, Stathopoulos P, Zhou J, Chen L, Gilbert T, Bolen C, et al.
J Immunol
. 2017 Jan;
198(4):1460-1473.
PMID: 28087666
Myasthenia gravis (MG) is a prototypical B cell-mediated autoimmune disease affecting 20-50 people per 100,000. The majority of patients fall into two clinically distinguishable types based on whether they produce...
9.
Cui A, Di Niro R, Vander Heiden J, Briggs A, Adams K, Gilbert T, et al.
J Immunol
. 2016 Oct;
197(9):3566-3574.
PMID: 27707999
Analyses of somatic hypermutation (SHM) patterns in B cell Ig sequences have important basic science and clinical applications, but they are often confounded by the intrinsic biases of SHM targeting...
10.
Tsioris K, Gupta N, Ogunniyi A, Zimnisky R, Qian F, Yao Y, et al.
Integr Biol (Camb)
. 2015 Oct;
7(12):1587-97.
PMID: 26481611
West Nile virus (WNV) infection is an emerging mosquito-borne disease that can lead to severe neurological illness and currently has no available treatment or vaccine. Using microengraving, an integrated single-cell...