Kevin C OConnor
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Explore the profile of Kevin C OConnor including associated specialties, affiliations and a list of published articles.
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117
Citations
4533
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Recent Articles
1.
Oh S, Khani-Habibabadi F, OConnor K, Payne A
Sci Adv
. 2025 Feb;
11(9):eadt0795.
PMID: 40020066
In acetylcholine receptor (AChR)-seropositive myasthenia gravis (MG), anti-AChR autoantibodies impair neuromuscular transmission and cause severe muscle weakness. MG therapies broadly suppress immune function, risking infections. We designed a chimeric autoantibody...
2.
Sun B, Fernandes D, Kienzler A, Paneva S, Harrison R, Ramanathan S, et al.
bioRxiv
. 2025 Jan;
PMID: 39868113
Autoimmunity affects 10% of the population. Within this umbrella, autoantibody-mediated diseases targeting one autoantigen provide a unique opportunity to comprehensively understand the developmental pathway of disease-causing B cells and autoantibodies....
3.
Detterbeck F, Kaminski H, Blasberg J, OConnor K
J Thorac Cardiovasc Surg
. 2024 Dec;
169(3):787-795.e2.
PMID: 39641701
No abstract available.
4.
Oh S, Mao X, Manfredo-Vieira S, Lee J, Patel D, Choi E, et al.
Nat Biotechnol
. 2024 Nov;
42(12):1923.
PMID: 39543316
No abstract available.
5.
Panicker A, OConnor K
Sci Immunol
. 2024 Oct;
9(100):eadt4136.
PMID: 39365872
Patients with autoimmune disease have exhausted antigen-specific T cells that remain capable of B cell support.
6.
Baxter L, Hopkins S, OConnor K, Pham M, Nowak R, Monson N, et al.
J Neuroimmunol
. 2024 Sep;
396:578454.
PMID: 39277987
Autoimmune autonomic ganglionopathy (AAG) is a rare disease wherein autoantibodies target the ganglionic acetylcholine receptor (gAChR). Current diagnosis in the United States depends upon clinical symptoms and positive autoantibody detection...
7.
Bennett J, Pittock S, Paul F, Kim H, Irani S, OConnor K, et al.
Ann Clin Transl Neurol
. 2024 Sep;
11(10):2792-2798.
PMID: 39222408
This post hoc analysis of the randomized, placebo-controlled N-MOmentum study (NCT02200770) of inebilizumab in neuromyelitis optica spectrum disorder (NMOSD) evaluated relationships between circulating B-cell subsets and aquaporin-4 immunoglobulin G (AQP4-lgG)...
8.
Holcomb J, Butler F, Schreiber M, Taylor A, Riggs L, Krohmer J, et al.
Transfusion
. 2024 Jul;
64(8):1543-1550.
PMID: 39031029
No abstract available.
9.
Wallace A, OConnor K
Sci Immunol
. 2024 Jun;
9(96):eadq7284.
PMID: 38848339
Whole-proteome autoantibody profiling reveals an immunological signature that predates the clinical onset of multiple sclerosis.
10.
Bodansky A, Yu D, Rallistan A, Kalaycioglu M, Boonyaratanakornkit J, Green D, et al.
J Clin Invest
. 2024 May;
134(13).
PMID: 38753445
Given the global surge in autoimmune diseases, it is critical to evaluate emerging therapeutic interventions. Despite numerous new targeted immunomodulatory therapies, comprehensive approaches to apply and evaluate the effects of...