Franco H A Leite
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Explore the profile of Franco H A Leite including associated specialties, affiliations and a list of published articles.
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16
Citations
166
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Recent Articles
1.
Barbosa D, do Bomfim M, de Oliveira T, da Silva A, Taranto A, Cruz J, et al.
Pharmaceuticals (Basel)
. 2023 Dec;
16(12).
PMID: 38139784
Alzheimer's disease causes chronic neurodegeneration and is the leading cause of dementia in the world. The causes of this disease are not fully understood but seem to involve two essential...
2.
de Almeida R, Barbosa D, do Bomfim M, Amparo J, Andrade B, Costa S, et al.
Pharmaceuticals (Basel)
. 2023 Jan;
16(1).
PMID: 36678592
The enhancement of cholinergic functions via acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibition is considered a valuable therapeutic strategy for the treatment of Alzheimer's disease. This study aimed to evaluate the...
3.
Neto M, Campos J, Cerqueira A, de Lima L, Da Costa G, Ramos R, et al.
Molecules
. 2022 Oct;
27(20).
PMID: 36296371
The Aedes aegypti mosquito is the main hematophagous vector responsible for arbovirus transmission in Brazil. The disruption of A. aegypti hematophagy remains one of the most efficient and least toxic...
4.
Da Costa G, Neto M, Da Silva A, De Sa E, Cancela L, Vega J, et al.
Int J Mol Sci
. 2022 Jul;
23(15).
PMID: 35897792
Aedes aegypti is the main vector that transmits viral diseases such as dengue, hemorrhagic dengue, urban yellow fever, zika, and chikungunya. Worldwide, many cases of dengue have been reported in...
5.
Mota T, Silva C, Conceicao M, Fraga D, Brodskyn C, Neto M, et al.
Acta Trop
. 2022 Feb;
229:106367.
PMID: 35167802
In the Americas, Lutzomyia longipalpis is the most relevant sand fly species for the transmission of visceral leishmaniasis. For its vector control in Brazil, insecticide spraying has not shown persistent...
6.
Cardona H, Froes T, Souza B, Leite F, Brandao H, Buaruang J, et al.
J Biomol Struct Dyn
. 2021 Aug;
40(22):11968-11976.
PMID: 34415221
Marine-derived fungi are a promising source of bioactive molecules, especially species from extreme habitats. Although several secondary metabolites such as meroterpenoids and alkaloids have been isolated from cultures of obtained...
7.
Almeida V, Dias E, Souza B, Cruz J, Santos C, Leite F, et al.
J Biomol Struct Dyn
. 2021 Mar;
40(16):7574-7583.
PMID: 33739225
This study aimed to evaluate the effect of a methoxylated fraction from Seub on myeloperoxidase (MPO)-chlorinating activity and subsequent assays for binding profile prediction. Therefore, the ethyl acetate extract of...
8.
Ferreira E, Silva L, Cruz J, Araujo P, Kimani N, Leite F, et al.
Curr Med Chem
. 2021 Feb;
28(29):5884-5895.
PMID: 33596793
This article presents a simplified view of integrins with emphasis on the α4 (α4β1/VLA-4) integrin. Integrins are heterodimeric proteins expressed on the cell surface of leukocytes that participate in a...
9.
Santos C, Santos K, Cruz J, Leite F, Borges R, Taft C, et al.
J Biomol Struct Dyn
. 2020 Apr;
39(9):3115-3127.
PMID: 32338151
Adenosine A receptor (AR) is the predominant receptor in immune cells, where its activation triggers cAMP-mediated immunosuppressive signaling and the underlying inhibition of T cells activation and T cells-induced effects...
10.
Santos K, Cruz J, Silva L, Ramos R, Neto M, Lobato C, et al.
Molecules
. 2020 Mar;
25(5).
PMID: 32164183
Adenosine Receptor Type 2A (AAR) plays a role in important processes, such as anti-inflammatory ones. In this way, the present work aimed to search for compounds by pharmacophore-based virtual screening....