Carlos H T P da Silva
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Explore the profile of Carlos H T P da Silva including associated specialties, affiliations and a list of published articles.
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21
Citations
231
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Recent Articles
1.
Villagra U, da Cunha B, Polachini G, Henrique T, Stefanini A, de Castro T, et al.
Genome Biol Evol
. 2024 May;
16(7).
PMID: 38752399
Alternative splicing is the process of generating different mRNAs from the same primary transcript, which contributes to increase the transcriptome and proteome diversity. Abnormal splicing has been associated with the...
2.
Correia L, Ferreira J, de Lima H, Silva G, da Silva C, de Molfetta F, et al.
J Mol Model
. 2022 Aug;
28(9):258.
PMID: 35978141
Search for new pharmacological alternatives for obesity is based on the design and development of compounds that can aid in weight loss so that they can be used safely and...
3.
Dos Santos I, Borges R, Silva G, de Lima L, Bastos R, Ramos R, et al.
Front Mol Biosci
. 2022 Jun;
9:836572.
PMID: 35720115
Skin Cancer (SC) is among the most common type of cancers worldwide. The search for SC therapeutics using molecular modeling strategies as well as considering natural plant-derived products seems to...
4.
Santos K, Cruz J, Silva L, Ramos R, Neto M, Lobato C, et al.
Molecules
. 2020 Mar;
25(5).
PMID: 32164183
Adenosine Receptor Type 2A (AAR) plays a role in important processes, such as anti-inflammatory ones. In this way, the present work aimed to search for compounds by pharmacophore-based virtual screening....
5.
Marino B, de Souza L, Sousa K, Ferreira J, Padilha E, da Silva C, et al.
Mini Rev Med Chem
. 2019 Nov;
20(9):754-767.
PMID: 31686637
Parkinson's Disease (PD) is the second most common neurodegenerative disease in the elderly population, with a higher prevalence in men, independent of race and social class; it affects approximately 1.5...
6.
Cruz J, Serafim R, da Silva G, Giuliatti S, Rosa J, Araujo Neto M, et al.
J Mol Model
. 2018 Aug;
24(9):225.
PMID: 30088101
Receptor-interacting protein kinase 2 (RIPK2) plays an essential role in autoimmune response and is suggested as a target for inflammatory diseases. A pharmacophore model was built from a dataset with...
7.
Cruz J, Neto M, Silva L, Ramos R, Costa J, Brasil D, et al.
Molecules
. 2018 Feb;
23(2).
PMID: 29463017
The Protein Kinase Receptor type 2 (RIPK2) plays an important role in the pathogenesis of inflammatory diseases; it signals downstream of the NOD1 and NOD2 intracellular sensors and promotes a...
8.
Ferreira J, Chaves G, Marino B, Sousa K, Souza L, Brito M, et al.
ChemMedChem
. 2017 Apr;
12(16):1408-1416.
PMID: 28417566
Cannabis sativa withdrawal syndrome is characterized mainly by psychological symptoms. By using computational tools, the aim of this study was to propose drug candidates for treating withdrawal syndrome based on...
9.
Pereira A, Santos G, Franco M, Federico L, da Silva C, Santos C
J Biomol Struct Dyn
. 2016 Dec;
36(2):318-334.
PMID: 28027711
Human dipeptidyl peptidase IV (hDDP-IV) has a considerable importance in inactivation of glucagon-like peptide-1, which is related to type 2 diabetes. One approach for the treatment is the development of...
10.
Moreira J, Pernomian L, Gomes M, Moreira R, do Prado A, da Silva C, et al.
Eur J Pharmacol
. 2016 Apr;
783:11-22.
PMID: 27118175
Diabetes mellitus is associated with reactive oxygen and nitrogen species accumulation. Behavioral stress increases nitric oxide production, which may trigger a massive impact on vascular cells and accelerate cardiovascular complications...