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Joaquin M Campos

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Citations 350
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Recent Articles
1.
Barbosa D, do Bomfim M, de Oliveira T, da Silva A, Taranto A, Cruz J, et al.
Pharmaceuticals (Basel) . 2023 Dec; 16(12). PMID: 38139784
Alzheimer's disease causes chronic neurodegeneration and is the leading cause of dementia in the world. The causes of this disease are not fully understood but seem to involve two essential...
2.
Santos C, Lobato C, Ota S, Silva R, Bittencourt R, Freitas J, et al.
Pharmaceuticals (Basel) . 2023 Nov; 16(11). PMID: 38004449
The design, synthesis, and evaluation of novel non-steroidal anti-inflammatory drugs (NSAIDs) with better activity and lower side effects are big challenges today. In this work, two 5-acetamido-2-hydroxy benzoic acid derivatives...
3.
Oliveira L, Lima L, Silva L, Cruz J, Ramos R, Lima L, et al.
Pharmaceuticals (Basel) . 2023 Oct; 16(10). PMID: 37895901
is a microorganism with high morbidity and mortality due to antibiotic-resistant strains, making the search for new therapeutic options urgent. In this context, computational drug design can facilitate the drug...
4.
Bastos R, de Lima L, Neto M, Maryam , Yousaf N, Cruz J, et al.
Int J Mol Sci . 2023 May; 24(10). PMID: 37240165
When an epidemic started in the Chinese city of Wuhan in December 2019, coronavirus was identified as the cause. Infection by the virus occurs through the interaction of viral S...
5.
Silva L, Ferreira E, Maryam , Espejo-Roman J, Costa G, Cruz J, et al.
Molecules . 2023 Feb; 28(3). PMID: 36770702
Acetylcholinesterase (AChE) enzymes play an essential role in the development of Alzheimer's disease (AD). Its excessive activity causes several neuronal problems, particularly psychopathies and neuronal cell death. A bioactive pose...
6.
de Almeida R, Barbosa D, do Bomfim M, Amparo J, Andrade B, Costa S, et al.
Pharmaceuticals (Basel) . 2023 Jan; 16(1). PMID: 36678592
The enhancement of cholinergic functions via acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibition is considered a valuable therapeutic strategy for the treatment of Alzheimer's disease. This study aimed to evaluate the...
7.
Neto M, Campos J, Cerqueira A, de Lima L, Da Costa G, Ramos R, et al.
Molecules . 2022 Oct; 27(20). PMID: 36296371
The Aedes aegypti mosquito is the main hematophagous vector responsible for arbovirus transmission in Brazil. The disruption of A. aegypti hematophagy remains one of the most efficient and least toxic...
8.
Da Costa G, Neto M, Da Silva A, De Sa E, Cancela L, Vega J, et al.
Int J Mol Sci . 2022 Jul; 23(15). PMID: 35897792
Aedes aegypti is the main vector that transmits viral diseases such as dengue, hemorrhagic dengue, urban yellow fever, zika, and chikungunya. Worldwide, many cases of dengue have been reported in...
9.
Silva R, Freitas H, Campos J, Kimani N, Silva C, Borges R, et al.
Int J Mol Sci . 2021 Nov; 22(21). PMID: 34769170
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has received global attention due to the serious threat it poses to public health. Since the outbreak...
10.
Cruz-Lopez O, Ner M, Nerin-Fonz F, Jimenez-Martinez Y, Araripe D, Marchal J, et al.
J Enzyme Inhib Med Chem . 2021 Jul; 36(1):1553-1563. PMID: 34251942
A series of 11 new substituted 1,5-dihydro-4,1-benzoxazepine derivatives was synthesised to study the influence of the methyl group in the 1-(benzenesulphonyl) moiety, the replacement of the purine by the benzotriazole...