Luciane B Silva
Overview
Explore the profile of Luciane B Silva including associated specialties, affiliations and a list of published articles.
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9
Citations
94
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Recent Articles
1.
Sanches V, Lobato C, Silva L, Dos Santos I, Barros E, Maciel A, et al.
Pharmaceuticals (Basel)
. 2024 Nov;
17(11).
PMID: 39598402
This study began with a search in three databases, totaling six libraries (ChemBridge-DIVERSet, ChemBridge-DIVERSet-EXP, Zinc_Drug Database, Zinc_Natural_Stock, Zinc_FDA_BindingDB, Maybridge) with approximately 2.5 million compounds with the aim of selecting potential...
2.
Oliveira L, Lima L, Silva L, Cruz J, Ramos R, Lima L, et al.
Pharmaceuticals (Basel)
. 2023 Oct;
16(10).
PMID: 37895901
is a microorganism with high morbidity and mortality due to antibiotic-resistant strains, making the search for new therapeutic options urgent. In this context, computational drug design can facilitate the drug...
3.
Galantamine Based Novel Acetylcholinesterase Enzyme Inhibitors: A Molecular Modeling Design Approach
Silva L, Ferreira E, Maryam , Espejo-Roman J, Costa G, Cruz J, et al.
Molecules
. 2023 Feb;
28(3).
PMID: 36770702
Acetylcholinesterase (AChE) enzymes play an essential role in the development of Alzheimer's disease (AD). Its excessive activity causes several neuronal problems, particularly psychopathies and neuronal cell death. A bioactive pose...
4.
Dos Santos I, Borges R, Silva G, de Lima L, Bastos R, Ramos R, et al.
Front Mol Biosci
. 2022 Jun;
9:836572.
PMID: 35720115
Skin Cancer (SC) is among the most common type of cancers worldwide. The search for SC therapeutics using molecular modeling strategies as well as considering natural plant-derived products seems to...
5.
Ferreira E, Silva L, Cruz J, Araujo P, Kimani N, Leite F, et al.
Curr Med Chem
. 2021 Feb;
28(29):5884-5895.
PMID: 33596793
This article presents a simplified view of integrins with emphasis on the α4 (α4β1/VLA-4) integrin. Integrins are heterodimeric proteins expressed on the cell surface of leukocytes that participate in a...
6.
Santos K, Cruz J, Silva L, Ramos R, Neto M, Lobato C, et al.
Molecules
. 2020 Mar;
25(5).
PMID: 32164183
Adenosine Receptor Type 2A (AAR) plays a role in important processes, such as anti-inflammatory ones. In this way, the present work aimed to search for compounds by pharmacophore-based virtual screening....
7.
Ferreira E, Silva L, Costa G, Costa J, Fujishima M, Leao R, et al.
Molecules
. 2019 Aug;
24(16).
PMID: 31416180
Leukemias are neoplasms that affect hematopoietic cells, which are developed by genetic alterations (mutations) that lead to the loss of proliferation control mechanisms (maturation and/or cell death). The α4β1 integrin...
8.
Bittencourt J, Neto M, Lacerda P, Bittencourt R, Silva R, Lobato C, et al.
Molecules
. 2019 Apr;
24(8).
PMID: 30991684
Inflammation is a complex reaction involving cellular and molecular components and an unspecific response to a specific aggression. The use of scientific and technological innovations as a research tool combining...
9.
Cruz J, Neto M, Silva L, Ramos R, Costa J, Brasil D, et al.
Molecules
. 2018 Feb;
23(2).
PMID: 29463017
The Protein Kinase Receptor type 2 (RIPK2) plays an important role in the pathogenesis of inflammatory diseases; it signals downstream of the NOD1 and NOD2 intracellular sensors and promotes a...