Faye M Drawnel
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Explore the profile of Faye M Drawnel including associated specialties, affiliations and a list of published articles.
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9
Citations
362
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Recent Articles
1.
Robinson E, Drawnel F, Mehdi S, Archer C, Liu W, Okkenhaug H, et al.
Cells
. 2022 Feb;
11(4).
PMID: 35203255
Heart failure is a leading cause of death that develops subsequent to deleterious hypertrophic cardiac remodelling. MAPK pathways play a key role in coordinating the induction of gene expression during...
2.
Korot E, Pontikos N, Drawnel F, Jaber A, Fu D, Zhang G, et al.
JAMA Ophthalmol
. 2021 Dec;
140(2):153-160.
PMID: 34913967
Importance: Telemedicine is accelerating the remote detection and monitoring of medical conditions, such as vision-threatening diseases. Meaningful deployment of smartphone apps for home vision monitoring should consider the barriers to...
3.
OLeary O, Schoetzau A, Amruthalingam L, Geber-Hollbach N, Plattner K, Jenoe P, et al.
Transl Vis Sci Technol
. 2020 Sep;
9(9):3.
PMID: 32879760
Purpose: Diagnosis of ocular graft-versus-host disease (oGVHD) is hampered by a lack of clinically-validated biomarkers. This study aims to predict disease severity on the basis of tear protein expression in...
4.
Feenstra D, Seleci M, Denk N, Fauser S, Drawnel F, Jayagopal A
Exp Eye Res
. 2018 Dec;
180:122-128.
PMID: 30582913
Retinal diseases such as proliferative diabetic retinopathy and neovascular AMD are characterized by the formation of new blood vessels. Current imaging techniques such as fluorescein and ICG angiography help to...
5.
Archer C, Robinson E, Drawnel F, Roderick H
Cell Signal
. 2017 Apr;
36:240-254.
PMID: 28412414
G-protein coupled receptor (GPCR) mediated activation of the MAPK signalling cascade is a key pathway in the induction of hypertrophic remodelling of the heart - a response to pathological cues...
6.
Drawnel F, Boccardo S, Prummer M, Delobel F, Graff A, Weber M, et al.
Cell Rep
. 2014 Dec;
9(3):810-21.
PMID: 25437537
Diabetic cardiomyopathy is a complication of type 2 diabetes, with known contributions of lifestyle and genetics. We develop environmentally and genetically driven in vitro models of the condition using human-induced-pluripotent-stem-cell-derived...
7.
Drawnel F, Wachten D, Molkentin J, Maillet M, Aronsen J, Swift F, et al.
J Cell Biol
. 2012 Nov;
199(5):783-98.
PMID: 23166348
Inositol 1,4,5'-triphosphate receptor II (IP(3)RII) calcium channel expression is increased in both hypertrophic failing human myocardium and experimentally induced models of the disease. The ectopic calcium released from these receptors...
8.
Drawnel F, Archer C, Roderick H
Br J Pharmacol
. 2012 Sep;
168(2):296-317.
PMID: 22946456
Unlabelled: Endothelin-1 (ET-1) is a critical autocrine and paracrine regulator of cardiac physiology and pathology. Produced locally within the myocardium in response to diverse mechanical and neurohormonal stimuli, ET-1 acutely...
9.
Higazi D, Fearnley C, Drawnel F, Talasila A, Corps E, Ritter O, et al.
Mol Cell
. 2009 Mar;
33(4):472-82.
PMID: 19250908
Ca(2+) elevations are fundamental to cardiac physiology-stimulating contraction and regulating the gene transcription that underlies hypertrophy. How Ca(2+) specifically controls gene transcription on the background of the rhythmic Ca(2+) increases...