Ivar Sjaastad
Overview
Explore the profile of Ivar Sjaastad including associated specialties, affiliations and a list of published articles.
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Articles
203
Citations
3404
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Recent Articles
1.
Hauge-Iversen I, Norden E, Melleby A, Espeland L, Zhang L, Sjaastad I, et al.
J Cardiovasc Magn Reson
. 2025 Feb;
27(1):101849.
PMID: 39894254
Background: Preclinical studies exploring the underlying mechanisms of elevated left ventricular (LV) chamber stiffness play a crucial role in developing new therapeutic strategies. However, there is a lack of systematic...
2.
Norden E, Bendiksen B, Bergo K, Espe E, McGinley G, Hasic A, et al.
ESC Heart Fail
. 2024 Dec;
PMID: 39696842
Aims: Sacubitril/valsartan (Sac/Val) is used for treatment of heart failure. The effect of Sac/Val on regional dysfunction following myocardial infarction (MI) remains uncertain. This study aimed at understanding the effects...
3.
Lunde I, Skrbic B, Sjaastad I, Christensen G, Carlson C, Tonnessen T
Front Mol Med
. 2024 Aug;
2:980717.
PMID: 39086965
Aortic valve stenosis (AS) is a major health problem. Extensive myocardial remodeling increases operative risk and might lead to incomplete reverse remodeling with persistent symptoms after aortic valve replacement (AVR);...
4.
Blom K, Kro G, Midtvedt K, Jenssen T, Reisaeter A, Rollag H, et al.
Front Immunol
. 2024 Jul;
15:1414830.
PMID: 39007131
Introduction: Cytomegalovirus (CMV) infection remains a challenge following kidney transplantation (KTx). Currently, CMV-IgG serostatus at transplantation is used to individualize CMV preventive strategies. We assessed the clinical utility of CMV-IGRA...
5.
Hou Y, Laasmaa M, Li J, Shen X, Manfra O, Norden E, et al.
Nat Cardiovasc Res
. 2024 May;
2(3):251-267.
PMID: 38803363
Ca sparks constitute the fundamental units of Ca release in cardiomyocytes. Here we investigate how ryanodine receptors (RyRs) collectively generate these events by employing a transgenic mouse with a photo-activated...
6.
Ruud M, Frisk M, Melleby A, Norseng P, Mohamed B, Li J, et al.
J Physiol
. 2024 Apr;
602(18):4487-4510.
PMID: 38686538
Mechanical load is a potent regulator of cardiac structure and function. Although high workload during heart failure is associated with disruption of cardiomyocyte t-tubules and Ca homeostasis, it remains unclear...
7.
Sasi A, Romaine A, Erusappan P, Melleby A, Hasic A, Dahl C, et al.
Matrix Biol Plus
. 2023 Dec;
19-20:100135.
PMID: 38076279
Cardiac fibrosis is a central pathological feature in several cardiac diseases, but the underlying molecular players are insufficiently understood. The extracellular matrix proteoglycan versican is elevated in heart failure and...
8.
Norden E, Veras I, Yadav P, Loken K, Dishington H, Thorstensen C, et al.
Lab Anim
. 2023 Sep;
58(1):34-43.
PMID: 37669442
Serum corticosterone, serum buprenorphine, body weight change, consumption of food and water and behaviour-based pain assessment were measured in catheterised and non-catheterised male Wistar rats undergoing myocardial infarct (MI) surgery...
9.
Vistnes M, Erusappan P, Sasi A, Norden E, Bergo K, Romaine A, et al.
Cardiovasc Res
. 2023 May;
119(10):1915-1927.
PMID: 37216909
Aims: Heart failure is a condition with high mortality rates, and there is a lack of therapies that directly target maladaptive changes in the extracellular matrix (ECM), such as fibrosis....
10.
Blom K, Birkeland G, Midtvedt K, Jenssen T, Reisaeter A, Rollag H, et al.
Transplantation
. 2023 May;
107(8):1846-1853.
PMID: 37211633
Background: Following kidney transplantation (KT), cytomegalovirus (CMV) infection remains an important challenge. Both prophylactic and preemptive antiviral protocols are used for CMV high-risk kidney recipients (donor seropositive/recipient seronegative; D+/R-). We...