Farrell MacKenzie
Overview
Explore the profile of Farrell MacKenzie including associated specialties, affiliations and a list of published articles.
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Articles
25
Citations
1233
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0
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Recent Articles
1.
Benfield C, MacKenzie F, Ritzefeld M, Mazzon M, Weston S, Tate E, et al.
Life Sci Alliance
. 2020 May;
3(6).
PMID: 32350036
No abstract available.
2.
Benfield C, MacKenzie F, Ritzefeld M, Mazzon M, Weston S, Tate E, et al.
Life Sci Alliance
. 2019 Dec;
3(1).
PMID: 31826928
Host interferon-induced transmembrane proteins (IFITMs) are broad-spectrum antiviral restriction factors. Of these, IFITM3 potently inhibits viruses that enter cells through acidic endosomes, many of which are zoonotic and emerging viruses...
3.
Tempel W, Grabovec I, MacKenzie F, Dichenko Y, Usanov S, Gilep A, et al.
J Lipid Res
. 2014 Jun;
55(9):1925-32.
PMID: 24927729
Hepatic conversion to bile acids is a major elimination route for cholesterol in mammals. CYP7A1 catalyzes the first and rate-limiting step in classic bile acid biosynthesis, converting cholesterol to 7α-hydroxycholesterol....
4.
Yantsevich A, Dichenko Y, MacKenzie F, Mukha D, Baranovsky A, Gilep A, et al.
FEBS J
. 2014 Feb;
281(6):1700-13.
PMID: 24491228
Oxysterols and neurosteroids are important signaling molecules produced by monooxygenases of the cytochrome P450 family that realize their effect through nuclear receptors. CYP7B1 catalyzes the 6- or 7-hydroxylation of both...
5.
Wang T, Xu C, Liu Y, Fan K, Li Z, Sun X, et al.
PLoS One
. 2013 Jan;
7(12):e52977.
PMID: 23285239
SUV39H1, the first identified histone lysine methyltransferase in human, is involved in chromatin modification and gene regulation. SUV39H1 contains a chromodomain in its N-terminus, which potentially plays a role in...
6.
Zhu H, Lee H, Tong Y, Hong B, Kim K, Shen Y, et al.
PLoS One
. 2012 Apr;
7(3):e33943.
PMID: 22470497
Kinesin-1 transports various cargos along the axon by interacting with the cargos through its light chain subunit. Kinesin light chains (KLC) utilize its tetratricopeptide repeat (TPR) domain to interact with...
7.
Liu K, Guo Y, Liu H, Bian C, Lam R, Liu Y, et al.
PLoS One
. 2012 Feb;
7(2):e30375.
PMID: 22363433
SMN (Survival motor neuron protein) was characterized as a dimethyl-arginine binding protein over ten years ago. TDRD3 (Tudor domain-containing protein 3) and SPF30 (Splicing factor 30 kDa) were found to...
8.
Ouyang H, Ali Y, Ravichandran M, Dong A, Qiu W, MacKenzie F, et al.
J Biol Chem
. 2011 Nov;
287(4):2317-27.
PMID: 22069321
The aggresome pathway is activated when proteasomal clearance of misfolded proteins is hindered. Misfolded polyubiquitinated protein aggregates are recruited and transported to the aggresome via the microtubule network by a...
9.
Artz J, Wernimont A, Allali-Hassani A, Zhao Y, Amani M, Lin Y, et al.
BMC Genomics
. 2011 Oct;
12:478.
PMID: 21962082
Background: Hundreds of millions of people are infected with cryptosporidiosis annually, with immunocompromised individuals suffering debilitating symptoms and children in socioeconomically challenged regions at risk of repeated infections. There is...
10.
Zhang W, Xu C, Bian C, Tempel W, Crombet L, MacKenzie F, et al.
Biochem Biophys Res Commun
. 2011 Sep;
413(1):58-61.
PMID: 21888896
DPF2 is an evolutionary highly conserved member of the d4-protein family characterized by an N-terminal 2/3 domain, a C2H2-type zinc finger (ZF), and a C-terminal tandem PHD zinc finger. DPF2...