Fabrizio dAdda di Fagagna
Overview
Explore the profile of Fabrizio dAdda di Fagagna including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
85
Citations
10242
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Trastus L, dAdda di Fagagna F
Nat Aging
. 2025 Mar;
PMID: 40038418
Cancer is an age-related disease, but the interplay between cancer and aging is complex and their shared molecular drivers are deeply intertwined. This Review provides an overview of how different...
2.
Fracassi G, Lorenzin F, Orlando F, Gioia U, DAmato G, Casaramona A, et al.
J Clin Invest
. 2024 Dec;
135(4).
PMID: 39718835
PARP inhibitors (PARPi) have received regulatory approval for the treatment of several tumors, including prostate cancer (PCa), and demonstrate remarkable results in the treatment of castration-resistant prostate cancer (CRPC) patients...
3.
Ogrodnik M, Carlos Acosta J, Adams P, dAdda di Fagagna F, Baker D, Bishop C, et al.
Cell
. 2024 Aug;
187(16):4150-4175.
PMID: 39121846
Cellular senescence is a cell fate triggered in response to stress and is characterized by stable cell-cycle arrest and a hypersecretory state. It has diverse biological roles, ranging from tissue...
4.
Wiley C, Hara E, dAdda di Fagagna F
Nat Aging
. 2024 Mar;
4(4):435-436.
PMID: 38486032
No abstract available.
5.
Rosso I, Jones-Weinert C, Rossiello F, Cabrini M, Brambillasca S, Munoz-Sagredo L, et al.
Nat Commun
. 2023 Nov;
14(1):7086.
PMID: 37925537
Alternative lengthening of telomeres (ALT) is a telomere maintenance mechanism activated in ~10-15% of cancers, characterized by telomeric damage. Telomeric damage-induced long non-coding RNAs (dilncRNAs) are transcribed at dysfunctional telomeres...
6.
Gioia U, Tavella S, Martinez-Orellana P, Cicio G, Colliva A, Ceccon M, et al.
Nat Cell Biol
. 2023 Mar;
25(4):550-564.
PMID: 36894671
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the RNA virus responsible for the coronavirus disease 2019 (COVID-19) pandemic. Although SARS-CoV-2 was reported to alter several cellular pathways, its impact...
7.
Falcinelli M, DellOmo G, Grassi E, Mariella E, Leto S, Scardellato S, et al.
Cell Death Dis
. 2023 Feb;
14(2):96.
PMID: 36759506
Telomere maintenance is necessary to maintain cancer cell unlimited viability. However, the mechanisms maintaining telomere length in colorectal cancer (CRC) have not been extensively investigated. Telomere maintenance mechanisms (TMM) include...
8.
Frittoli E, Palamidessi A, Iannelli F, Zanardi F, Villa S, Barzaghi L, et al.
Nat Mater
. 2023 Jan;
22(3):400.
PMID: 36702890
No abstract available.
9.
Frittoli E, Palamidessi A, Iannelli F, Zanardi F, Villa S, Barzaghi L, et al.
Nat Mater
. 2022 Dec;
22(5):644-655.
PMID: 36581770
The process in which locally confined epithelial malignancies progressively evolve into invasive cancers is often promoted by unjamming, a phase transition from a solid-like to a liquid-like state, which occurs...
10.
Buemi V, Schillaci O, Santorsola M, Bonazza D, Broccia P, Zappone A, et al.
Nat Commun
. 2022 Apr;
13(1):2302.
PMID: 35484160
Pathways that direct the selection of the telomerase-dependent or recombination-based, alternative lengthening of telomere (ALT) maintenance pathway in cancer cells are poorly understood. Using human lung cancer cells and tumor...