Fabio Iannelli
Overview
Explore the profile of Fabio Iannelli including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
1257
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0
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Recent Articles
1.
Voena C, Ambrogio C, Iannelli F, Chiarle R
Nat Rev Cancer
. 2025 Mar;
PMID: 40055571
Anaplastic lymphoma kinase (ALK) is a receptor tyrosine kinase (RTK) that acts as an oncogenic driver in solid and haematological malignancies in both children and adults. Although ALK-expressing (ALK) tumours...
2.
Tamburri S, Zucchelli C, Matafora V, Zapparoli E, Jevtic Z, Farris F, et al.
Nucleic Acids Res
. 2024 Dec;
53(4).
PMID: 39718989
SP140, a lymphocytic-restricted protein, is an epigenetic reader working as a corepressor of genes implicated in inflammation and orchestrating macrophage transcriptional programs to maintain cellular identity. Reduced SP140 expression is...
3.
Ligorio F, Vingiani A, Torelli T, Sposetti C, Drufuca L, Iannelli F, et al.
Cell Metab
. 2024 Dec;
37(2):330-344.e7.
PMID: 39694040
In preclinical experiments, cyclic fasting-mimicking diets (FMDs) showed broad anticancer effects in combination with chemotherapy. Among different tumor types, triple-negative breast cancer (TNBC) is exquisitely sensitive to FMD. However, the...
4.
Kakogiannos N, Scalise A, Martini E, Maderna C, Benvenuto A, DAntonio M, et al.
J Clin Invest
. 2024 Aug;
134(15).
PMID: 39087467
The blood-brain barrier (BBB) acquires unique properties to regulate neuronal function during development. The formation of the BBB, which occurs in tandem with angiogenesis, is directed by the Wnt/β-catenin signaling...
5.
Bastianello G, Kidiyoor G, Lowndes C, Li Q, Bonnal R, Godwin J, et al.
Proc Natl Acad Sci U S A
. 2024 Jul;
121(29):e2404551121.
PMID: 38990945
Confined cell migration hampers genome integrity and activates the ATR and ATM mechano-transduction pathways. We investigated whether the mechanical stress generated by metastatic interstitial migration contributes to the enhanced chromosomal...
6.
Crestani M, Kakogiannos N, Iori S, Iannelli F, Dini T, Maderna C, et al.
Small Methods
. 2024 May;
8(12):e2400210.
PMID: 38747088
Glioblastomas exhibit remarkable heterogeneity at various levels, including motility modes and mechanoproperties that contribute to tumor resistance and recurrence. In a recent study using gridded micropatterns mimicking the brain vasculature,...
7.
Hershey B, Barozzi S, Orsenigo F, Pompei S, Iannelli F, Kamrad S, et al.
Sci Adv
. 2023 Sep;
9(37):eadh4184.
PMID: 37713487
Cancers feature substantial intratumoral heterogeneity of genetic and phenotypically distinct lineages. Although interactions between coexisting lineages are emerging as a potential contributor to tumor evolution, the extent and nature of...
8.
Poli A, Pennacchio F, Ghisleni A, Di Gennaro M, Lecacheur M, Nastaly P, et al.
Nat Commun
. 2023 Mar;
14(1):1432.
PMID: 36918565
Phosphatidylinositol-5-phosphate (PtdIns5P)-4-kinases (PIP4Ks) are stress-regulated phosphoinositide kinases able to phosphorylate PtdIns5P to PtdIns(4,5)P2. In cancer patients their expression is typically associated with bad prognosis. Among the three PIP4K isoforms expressed...
9.
Frittoli E, Palamidessi A, Iannelli F, Zanardi F, Villa S, Barzaghi L, et al.
Nat Mater
. 2023 Jan;
22(3):400.
PMID: 36702890
No abstract available.
10.
Frittoli E, Palamidessi A, Iannelli F, Zanardi F, Villa S, Barzaghi L, et al.
Nat Mater
. 2022 Dec;
22(5):644-655.
PMID: 36581770
The process in which locally confined epithelial malignancies progressively evolve into invasive cancers is often promoted by unjamming, a phase transition from a solid-like to a liquid-like state, which occurs...