F C Nelson
Overview
Explore the profile of F C Nelson including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
215
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0
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Recent Articles
1.
Nelson F, Zask A
Expert Opin Investig Drugs
. 2005 Jul;
8(4):383-92.
PMID: 15992086
No abstract available.
2.
Levin J, Chen J, Du M, Nelson F, Killar L, Skala S, et al.
Bioorg Med Chem Lett
. 2002 Apr;
12(8):1199-202.
PMID: 11934588
The SAR of a series of potent sulfonamide hydroxamate TACE inhibitors bearing novel acetylenic P1' groups was explored. In particular, compound 4t bearing a butynyloxy P1' moiety has excellent in...
3.
Levin J, Chen J, Du M, Nelson F, Wehr T, DiJoseph J, et al.
Bioorg Med Chem Lett
. 2001 Oct;
11(22):2975-8.
PMID: 11677139
Anthranilic acid derivatives bearing basic amines were prepared and evaluated in vitro and in vivo as inhibitors of MMP-1, MMP-9, MMP-13, and TACE. Piperazine 4u has been identified as a...
4.
Levin J, Chen J, Du M, Hogan M, Kincaid S, Nelson F, et al.
Bioorg Med Chem Lett
. 2001 Aug;
11(16):2189-92.
PMID: 11514167
A novel series of anthranilic acid-based inhibitors of MMP-1, MMP-9, MMP-13, and TACE was prepared and evaluated. Selective inhibitors of MMP-9, MMP-13, and TACE were identified, including the potent, orally...
5.
Levin J, Gu Y, Nelson F, Zask A, DiJoseph J, Sharr M, et al.
Bioorg Med Chem Lett
. 2001 Feb;
11(2):239-42.
PMID: 11206468
Heteroaryl and cycloalkyl sulfonamide-hydroxamic acid MMP inhibitors were investigated. Of these, the pyridyl analogue 2 is the most potent and selective inhibitor of MMP-9 and MMP-13 in vitro.
6.
Skotnicki J, Zask A, Nelson F, Albright J, Levin J
Ann N Y Acad Sci
. 1999 Jul;
878:61-72.
PMID: 10415720
Experimental evidence confirms that the matrix metalloproteinases (MMPs) play a fundamental role in a wide variety of pathologic conditions that involve connective tissue destruction including osteoarthritis and rheumatoid arthritis, tumor...
7.
Nelson F, Stachel S, Eng C, Sehgal S
Bioorg Med Chem Lett
. 1999 Feb;
9(2):295-300.
PMID: 10021948
A novel series of rapamycin derivatives with modifications in the C(22)-C(27) region has been prepared. These compounds are evaluated for their ability to prevent ring fragmentation while still retaining immunosuppressive...
8.
Jeffery P, Wardlaw A, Nelson F, Collins J, Kay A
Am Rev Respir Dis
. 1989 Dec;
140(6):1745-53.
PMID: 2690708
Little is known of the structural changes in mild asthma. We have studied the light and electron microscopic structure of lobar bronchial biopsies taken at fiberoptic bronchoscopy from 11 atopic...
9.
Ruhnke H, Thawley D, Nelson F
Can J Comp Med
. 1976 Apr;
40(2):142-8.
PMID: 1000385
Bovine mastitis caused by Mycoplasma agalactiae subsp. bovis was first diagnosed in 16 of 55 cows in an Ontario herd in Feburary 1972. A total of 182 of 598 (30.4%)...
10.
Dodds J, Nelson F, Meads E, Hebert C
Can Vet J
. 1969 Jul;
10(7):188-90.
PMID: 5193914
No abstract available.