Ewa Szymanska
Overview
Explore the profile of Ewa Szymanska including associated specialties, affiliations and a list of published articles.
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Articles
61
Citations
625
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Recent Articles
1.
Jastrzebska-Wiesek M, Garbo S, Cios A, Wilczynska-Zawal N, Partyka A, Honkisz-Orzechowska E, et al.
ACS Chem Neurosci
. 2025 Feb;
PMID: 40020084
Among serotonin receptors, the 5-HT subtype is an important protein target and its ligands may play a key role in the innovative treatment of cognitive disorders. This study aimed to...
2.
Tarapata J, Szymanska E, van der Meulen L, Miltenburg J, Huppertz T
Foods
. 2025 Jan;
14(2).
PMID: 39856832
This study examined how temperature, cheese mass and moisture content impact moisture loss rate in various cheeses during baking. Understanding these factors is essential for determining the browning properties of...
3.
Pyka P, Garbo S, Murzyn A, Satala G, Janusz A, Gorka M, et al.
Bioorg Chem
. 2024 Jul;
151:107668.
PMID: 39079393
An increasing number of drugs introduced to the market and numerous repositories of compounds with confirmed activity have posed the need to revalidate the state-of-the-art rules that determine the ranges...
4.
Chalupnik P, Marek A, Hovah M, Pickering D, Temperini P, Donbosco S, et al.
J Labelled Comp Radiopharm
. 2024 Feb;
67(4):120-130.
PMID: 38332677
Kainate receptors play a crucial role in mediating synaptic transmission within the central nervous system. However, the lack of selective pharmacological tool compounds for the GluK3 subunit represents a significant...
5.
Pyka P, Haberek W, Wiecek M, Szymanska E, Ali W, Cios A, et al.
J Med Chem
. 2024 Jan;
67(2):1580-1610.
PMID: 38190615
Alzheimer's disease (AD) has a complex and not-fully-understood etiology. Recently, the serotonin receptor 5-HT emerged as a promising target for AD treatment; thus, here a new series of 5-HTR ligands...
6.
Nitek W, Szymanska E, Tejchman W, Zeslawska E
Acta Crystallogr C Struct Chem
. 2023 Aug;
79(Pt 9):334-343.
PMID: 37549023
5-Arylidene derivatives of rhodanine show various biological activities. The new crystal structures of five derivatives investigated towards ABCB1 efflux pump modulation are reported, namely, 2-[5-([1,1'-biphenyl]-4-ylmethylidene]-4-oxo-2-thioxothiazolidin-3-yl)acetic acid dimethyl sulfoxide monosolvate, CHNOS·CHOS...
7.
Chalupnik P, Vialko A, Pickering D, Nielsen B, Bay Y, Kristensen A, et al.
ChemMedChem
. 2023 Jun;
18(18):e202300278.
PMID: 37387321
Kainate receptors are a class of ionotropic glutamate receptors that respond to the excitatory neurotransmitter glutamate in the central nervous system and play an important role in the development of...
8.
Lazewska D, Wiecek M, Satala G, Chalupnik P, Zeslawska E, Honkisz-Orzechowska E, et al.
Molecules
. 2023 Feb;
28(3).
PMID: 36770774
Since the number of people with Alzheimer's disease (AD) continues to rise, new and effective drugs are urgently needed to not only slow down the progression of the disease, but...
9.
Chalupnik P, Szymanska E
Int J Mol Sci
. 2023 Feb;
24(3).
PMID: 36768227
Since the 1990s, ionotropic glutamate receptors have served as an outstanding target for drug discovery research aimed at the discovery of new neurotherapeutic agents. With the recent approval of perampanel,...
10.
Ali W, Garbo S, Kincses A, Nove M, Spengler G, Di Bello E, et al.
Eur J Med Chem
. 2022 Sep;
243:114761.
PMID: 36179403
Lymphomas are still difficult to treat even with modern therapies as, among others, multidrug resistance (MDR) is often counteracting a successful cancer therapy. P-gp/ABC-transporters are well-known for their crucial role...