Ewa C S Ellis
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Explore the profile of Ewa C S Ellis including associated specialties, affiliations and a list of published articles.
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20
Citations
413
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Recent Articles
1.
Zimmer C, von Seth E, Buggert M, Strauss O, Hertwig L, Nguyen S, et al.
Sci Transl Med
. 2021 Jun;
13(599).
PMID: 34162753
The human biliary system, a mucosal barrier tissue connecting the liver and intestine, is an organ often affected by serious inflammatory and malignant diseases. Although these diseases are linked to...
2.
Johansson H, Sondergaard J, Jorns C, Kutter C, Ellis E
Front Endocrinol (Lausanne)
. 2021 Mar;
11:554922.
PMID: 33692750
Bile acids (BAs) are detergents essential for intestinal absorption of lipids. Disruption of BA homeostasis can lead to severe liver damage. BA metabolism is therefore under strict regulation by sophisticated...
3.
Minniti M, Pedrelli M, Vedin L, Delbes A, Denis R, Oorni K, et al.
Hepatology
. 2019 Dec;
72(2):656-670.
PMID: 31785104
Background And Aims: Genetically modified mice have been used extensively to study human disease. However, the data gained are not always translatable to humans because of major species differences. Liver-humanized...
4.
Gnocchi D, Ellis E, Johansson H, Eriksson M, Bruscalupi G, Steffensen K, et al.
Mol Cell Endocrinol
. 2019 Oct;
499:110604.
PMID: 31580898
Until three decades, ago 3,5-diiodothyronine (3,5-T) and 3,3'-diiodothyronine (3,3'-T) were considered products of thyroid hormone catabolism without biological activity. Some metabolic effects have been described in rodents, but the physiological...
5.
Karadagi A, Johansson H, Zemack H, Salipalli S, Mork L, Kannisto K, et al.
PLoS One
. 2017 May;
12(5):e0177279.
PMID: 28486562
The main goal of the therapy with purified human plasma alpha1-antitrypsin (A1AT) is to increase A1AT levels and to prevent lungs from elastolytic activity in patients with PiZZ (Glu342Lys) A1AT...
6.
Mork L, Strom S, Mode A, Ellis E
J Clin Exp Hepatol
. 2016 Aug;
6(2):87-93.
PMID: 27493455
Background: Primary human hepatocytes offer the best human in vitro model for studies on human liver cell metabolism. Investigators use a variety of different media supplements and matrix biocoatings and...
7.
Johansson H, Ellis E
Methods Mol Biol
. 2015 Aug;
1250:323-31.
PMID: 26272155
Primary hepatocytes isolated from human, mouse and rat liver as well as cell lines, such as HepG2 cells, are frequently used in vitro systems in liver research. In regenerative medicine,...
8.
Gramignoli R, Tahan V, Dorko K, Venkataramanan R, Fox I, Ellis E, et al.
Cell Transplant
. 2014 Apr;
23(12):1545-56.
PMID: 24702711
Transplantation of human hepatocytes (HTx) has gained recognition as a bridge to, or an alternative to, orthotopic liver transplantation for patients with acute liver failure or genetic defects in liver...
9.
Ellis E, Naugler W, Nauglers S, Parini P, Mork L, Jorns C, et al.
PLoS One
. 2013 Nov;
8(11):e78550.
PMID: 24223822
Objective: Rodents are poor model for human hyperlipidemias because total cholesterol and low density lipoprotein levels are very low on a normal diet. Lipoprotein metabolism is primarily regulated by hepatocytes...
10.
Gramignoli R, Tahan V, Dorko K, Skvorak K, Hansel M, Zhao W, et al.
Stem Cell Res
. 2013 May;
11(1):563-73.
PMID: 23644508
Unlabelled: Domino liver transplantation is a method used to increase the number of liver grafts available for orthotopic liver transplantation (OLT). Reports indicate that livers from patients with metabolic liver...