Stephen C Strom
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Explore the profile of Stephen C Strom including associated specialties, affiliations and a list of published articles.
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119
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4763
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Recent Articles
1.
Schulze R, Strom S, Nyberg S
Hepatology
. 2023 Dec;
79(5):973-975.
PMID: 38085850
No abstract available.
2.
Gramignoli R, Ranade A, Venkataramanan R, Strom S
Int J Mol Sci
. 2022 Dec;
23(23).
PMID: 36499207
Three decades of hepatocyte transplantation have confirmed such a cell-based approach as an adjunct or alternative treatment to solid organ transplantation. Donor cell survival and engraftment were indirectly measured by...
3.
Zabulica M, Jakobsson T, Ravaioli F, Vosough M, Gramignoli R, Ellis E, et al.
Int J Mol Sci
. 2021 Feb;
22(3).
PMID: 33530582
Urea cycle disorders are enzymopathies resulting from inherited deficiencies in any genes of the cycle. In severe cases, currently available therapies are marginally effective, with liver transplantation being the only...
4.
Zabulica M, Srinivasan R, Akcakaya P, Allegri G, Bestas B, Firth M, et al.
Mol Ther
. 2021 Jan;
29(5):1903-1917.
PMID: 33484963
Ornithine transcarbamylase deficiency (OTCD) is a monogenic disease of ammonia metabolism in hepatocytes. Severe disease is frequently treated by orthotopic liver transplantation. An attractive approach is the correction of a...
5.
Srinivasan R, Strom S, Gramignoli R
Cells
. 2020 Jul;
9(7).
PMID: 32679793
Perinatal stem cells and epithelial cells isolated from full term amnion membrane, in particular, have attracted interest over the last decade, as a promising source of multipotent cells for cellular...
6.
Minniti M, Pedrelli M, Vedin L, Delbes A, Denis R, Oorni K, et al.
Hepatology
. 2019 Dec;
72(2):656-670.
PMID: 31785104
Background And Aims: Genetically modified mice have been used extensively to study human disease. However, the data gained are not always translatable to humans because of major species differences. Liver-humanized...
7.
Zabulica M, Srinivasan R, Vosough M, Hammarstedt C, Wu T, Gramignoli R, et al.
Stem Cells Dev
. 2019 May;
28(14):907-919.
PMID: 31122128
Differentiation of stem cells to hepatocyte-like cells (HLCs) holds great promise for basic research, drug and toxicological investigations, and clinical applications. There are currently no protocols for the production of...
8.
Vosough M, Ravaioli F, Zabulica M, Capri M, Garagnani P, Franceschi C, et al.
PLoS One
. 2019 Apr;
14(4):e0215490.
PMID: 31022207
Induced pluripotent stem cell (iPSC)-technology is an important platform in medicine and disease modeling. Physiological degeneration and disease onset are common occurrences in the aging population. iPSCs could offer regenerative...
9.
Srinivasan R, Zabulica M, Hammarstedt C, Wu T, Gramignoli R, Kannisto K, et al.
J Inherit Metab Dis
. 2019 Mar;
42(6):1054-1063.
PMID: 30843237
A liver-humanized mouse model for CPS1-deficiency was generated by the high-level repopulation of the mouse liver with CPS1-deficient human hepatocytes. When compared with mice that are highly repopulated with CPS1-proficient...
10.
Morandi F, Horenstein A, Quarona V, Faini A, Castella B, Srinivasan R, et al.
J Immunol
. 2018 Dec;
202(3):724-735.
PMID: 30587530
This study investigates the mechanism(s) underlying the immunoregulatory activities of placenta-derived human amnion epithelial cells (hAEC). The working hypothesis is that NAD and ATP, along with ectoenzymes involved in their...