Ethan Dmitrovsky
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Explore the profile of Ethan Dmitrovsky including associated specialties, affiliations and a list of published articles.
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91
Citations
3238
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Recent Articles
1.
Wu W, Luke B, Wu X, Lee J, Yi Y, Okpechi S, et al.
JNCI Cancer Spectr
. 2024 Sep;
8(5).
PMID: 39270065
Background: The consequence of diabetes on lung cancer overall survival (OS) is debated. This retrospective study used 2 large lung cancer databases to assess comprehensively diabetes effects on lung cancer...
2.
Chen Z, Liu X, Kawakami M, Liu X, Baker A, Bhatawadekar A, et al.
Cancer Biol Ther
. 2023 Nov;
24(1):2279241.
PMID: 38031910
Cyclin-dependent Kinase 2 (CDK2) inhibition prevents supernumerary centrosome clustering. This causes multipolarity, anaphase catastrophe and apoptotic death of aneuploid cancers. This study elucidated how CDK2 antagonism affected centrosome stoichiometry. Focused...
3.
Wei C, Huang L, Kreh B, Liu X, Tyutyunyk-Massey L, Kawakami M, et al.
Sci Rep
. 2023 Sep;
13(1):14907.
PMID: 37689790
All-trans-retinoic acid (ATRA), the retinoic acid receptors (RARs) agonist, regulates cell growth, differentiation, immunity, and survival. We report that ATRA-treatment repressed cancer growth in syngeneic immunocompetent, but not immunodeficient mice....
4.
Roszik J, Lee J, Wu Y, Liu X, Kawakami M, Kurie J, et al.
Cancer Res Commun
. 2022 Jul;
2(7):590-601.
PMID: 35832288
Inflammation is a cancer hallmark. Nonsteroidal anti-inflammatory drugs (NSAIDs) improve overall survival (OS) in certain cancers. Real-world studies explored here if NSAIDs improve non-small cell lung cancer (NSCLC) OS. Analyses...
5.
Chen Z, Zheng L, Chen Y, Liu X, Kawakami M, Mustachio L, et al.
Cancer Biol Ther
. 2022 Apr;
23(1):265-280.
PMID: 35387560
Cancer metastasis is a major cause of cancer-related mortality. Strategies to reduce metastases are needed especially in lung cancer, the most common cause of cancer mortality. We previously reported increased...
6.
Liu X, Lu Y, Chen Z, Liu X, Hu W, Zheng L, et al.
Mol Cancer Res
. 2020 Dec;
19(4):667-677.
PMID: 33380466
Ubiquitin specific peptidase 18 (USP18), previously known as UBP43, is the IFN-stimulated gene 15 (ISG15) deconjugase. USP18 removes ISG15 from substrate proteins. This study reports that USP18-null mice (vs. wild-type...
7.
Kawakami M, Mustachio L, Chen Y, Chen Z, Liu X, Wei C, et al.
Mol Cancer Ther
. 2020 Dec;
20(3):477-489.
PMID: 33277443
Cyclin-dependent kinase 2 (CDK2) antagonism inhibits clustering of excessive centrosomes at mitosis, causing multipolar cell division and apoptotic death. This is called anaphase catastrophe. To establish induced anaphase catastrophe as...
8.
Nilsson M, Sun H, Robichaux J, Pfeifer M, McDermott U, Travers J, et al.
Sci Transl Med
. 2020 Sep;
12(559).
PMID: 32878980
Acquired resistance to tyrosine kinase inhibitors (TKIs) of epidermal growth factor receptor (EGFR) remains a clinical challenge. Especially challenging are cases in which resistance emerges through EGFR-independent mechanisms, such as...
9.
Dmitrovsky E, Kawakami M, Liu X, Freemantle S, Kurie J
Trans Am Clin Climatol Assoc
. 2020 Jul;
131:82-94.
PMID: 32675848
Cancer cells are genetically unstable and often have supernumerary centrosomes. When supernumerary centrosome clustering is inhibited at mitosis, multipolar cell division is forced, triggering apoptosis in daughter cells. This proapoptotic...
10.