Eryn E Dixon
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Explore the profile of Eryn E Dixon including associated specialties, affiliations and a list of published articles.
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14
Citations
247
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Recent Articles
1.
Muto Y, Dixon E, Yoshimura Y, Ledru N, Kirita Y, Wu H, et al.
Sci Adv
. 2024 Aug;
10(32):eado2849.
PMID: 39110788
Acute kidney injury (AKI) causes epithelial damage followed by subsequent repair. While successful repair restores kidney function, this process is often incomplete and can lead to chronic kidney disease (CKD)...
2.
Wu H, Dixon E, Xuanyuan Q, Guo J, Yoshimura Y, Debashish C, et al.
Nat Commun
. 2024 Feb;
15(1):1396.
PMID: 38360882
Emerging spatially resolved transcriptomics technologies allow for the measurement of gene expression in situ at cellular resolution. We apply direct RNA hybridization-based in situ sequencing (dRNA HybISS, Cartana part of...
3.
Muto Y, Dixon E, Yoshimura Y, Ledru N, Kirita Y, Wu H, et al.
bioRxiv
. 2024 Feb;
PMID: 38328130
Acute kidney injury (AKI) causes epithelial damage followed by subsequent repair. While successful repair restores kidney function, this process is often incomplete and can lead to chronic kidney disease (CKD)...
4.
Mosaic loss of Y chromosome is associated with aging and epithelial injury in chronic kidney disease
Wilson P, Verma A, Yoshimura Y, Muto Y, Li H, Malvin N, et al.
Genome Biol
. 2024 Jan;
25(1):36.
PMID: 38287344
Background: Mosaic loss of Y chromosome (LOY) is the most common chromosomal alteration in aging men. Here, we use single-cell RNA and ATAC sequencing to show that LOY is present...
5.
Jung H, Dixon E, Coleman R, Watnick T, Reiter J, Outeda P, et al.
Physiol Genomics
. 2023 Sep;
55(11):565-577.
PMID: 37720991
Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations in polycystin genes, and , but the underlying pathogenic mechanisms are poorly understood. To identify genes and pathways that operate...
6.
Muto Y, Dixon E, Yoshimura Y, Wu H, Omachi K, Ledru N, et al.
Nat Commun
. 2022 Oct;
13(1):6497.
PMID: 36310237
Autosomal dominant polycystic kidney disease (ADPKD) is the leading genetic cause of end stage renal disease characterized by progressive expansion of kidney cysts. To better understand the cell types and...
7.
Li H, Dixon E, Wu H, Humphreys B
Cell Metab
. 2022 Oct;
34(12):1977-1998.e9.
PMID: 36265491
The underlying cellular events driving kidney fibrogenesis and metabolic dysfunction are incompletely understood. Here, we employed single-cell combinatorial indexing RNA sequencing to analyze 24 mouse kidneys from two fibrosis models....
8.
Dixon E, Bradford S, Humphreys B
Cell Stem Cell
. 2022 Jul;
29(7):1011-1012.
PMID: 35803221
In this issue of Cell Stem Cell, Tran and colleagues develop a platform for differentiating thousands of miniature kidney organoids consisting of one or two nephron-like structures each. They use...
9.
Dixon E, Wu H, Sulvaran-Guel E, Guo J, Humphreys B
Kidney Int
. 2022 Jul;
102(3):482-491.
PMID: 35788360
Defining changes in gene expression during health and disease is critical for the understanding of human physiology. In recent years, single-cell/nuclei RNA sequencing (sc/snRNAseq) has revolutionized the definition and discovery...
10.
Choudhury M, Li Y, Mistriotis P, Vasconcelos A, Dixon E, Yang J, et al.
Nat Commun
. 2022 Apr;
13(1):2317.
PMID: 35484146
The role of mechanical forces driving kidney epithelial fluid transport and morphogenesis in kidney diseases is unclear. Here, using a microfluidic platform to recapitulate fluid transport activity of kidney cells,...