Erwin J G Peterman
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Explore the profile of Erwin J G Peterman including associated specialties, affiliations and a list of published articles.
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105
Citations
2758
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Recent Articles
21.
Meijering A, Sarlos K, Nielsen C, Witt H, Harju J, Kerklingh E, et al.
Nature
. 2022 May;
605(7910):545-550.
PMID: 35508652
In preparation for mitotic cell division, the nuclear DNA of human cells is compacted into individualized, X-shaped chromosomes. This metamorphosis is driven mainly by the combined action of condensins and...
22.
Bakx J, Biebricher A, King G, Christodoulis P, Sarlos K, Bizard A, et al.
Nat Commun
. 2022 Feb;
13(1):584.
PMID: 35102151
Topoisomerase IIIα is a type 1A topoisomerase that forms a complex with RMI1 and RMI2 called TRR in human cells. TRR plays an essential role in resolving DNA replication and...
23.
Zhang Z, Danne N, Meddens B, Heller I, Peterman E
Proc Natl Acad Sci U S A
. 2021 Nov;
118(45).
PMID: 34732580
Intraflagellar transport (IFT), a bidirectional intracellular transport mechanism in cilia, relies on the cooperation of kinesin-2 and IFT-dynein motors. In chemosensory cilia, motors undergo rapid turnarounds to effectively work together...
24.
Backer A, King G, Biebricher A, Shepherd J, Noy A, Leake M, et al.
J Phys Chem B
. 2021 Jul;
125(30):8351-8361.
PMID: 34309392
The combination of DNA force spectroscopy and polarization microscopy of fluorescent DNA intercalator dyes can provide valuable insights into the structure of DNA under tension. These techniques have previously been...
25.
Spakman D, Bakx J, Biebricher A, Peterman E, Wuite G, King G
Nucleic Acids Res
. 2021 May;
49(10):5470-5492.
PMID: 33963870
Topoisomerases are essential enzymes that regulate DNA topology. Type 1A family topoisomerases are found in nearly all living organisms and are unique in that they require single-stranded (ss)DNA for activity....
26.
VAN Krugten J, Taris K, Peterman E
J Microsc
. 2020 Sep;
281(3):214-223.
PMID: 32949409
Live observation of biological phenomena in the context of living organisms can provide important insights in the mechanisms of these phenomena. However, the spatially complex and dynamic physiology of multicellular...
27.
Kushwaha V, Peterman E
Biochem Biophys Res Commun
. 2020 Jul;
529(3):812-818.
PMID: 32620235
Biophysical studies of the mechanochemical cycle of kinesin motors are essential for understanding the mechanism of energy conversion. Here, we report a systematic study of the impact of temperature on...
28.
Spakman D, King G, Peterman E, Wuite G
Sci Rep
. 2020 Jun;
10(1):9903.
PMID: 32555215
As the basic building blocks of chromatin, nucleosomes play a key role in dictating the accessibility of the eukaryotic genome. Consequently, nucleosomes are involved in essential genomic transactions such as...
29.
Mitra A, Peterman E
Curr Biol
. 2020 Mar;
30(6):R282-R285.
PMID: 32208157
The velocity of intraflagellar transport among evolutionarily distant organisms differs substantially, while the transport machinery is well conserved. A new in vitro study finds that the velocity difference is encoded...
30.
Kushwaha V, Acar S, Miedema D, Denisov D, Schall P, Peterman E
PLoS One
. 2020 Feb;
15(2):e0228930.
PMID: 32053680
Intraflagellar transport (IFT) in C. elegans chemosensory cilia is an example of functional coordination and cooperation of two motor proteins with distinct motility properties operating together in large groups to...