Andreas S Biebricher
Overview
Explore the profile of Andreas S Biebricher including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
184
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Recent Articles
1.
Bergamaschi G, Biebricher A, Witt H, Byfield F, Seymonson X, Storm C, et al.
Cell Rep
. 2024 Oct;
43(10):114852.
PMID: 39412986
A quantitative description of nuclear mechanics is crucial for understanding its role in force sensing within eukaryotic cells. Recent studies indicate that the chromatin within the nucleus cannot be treated...
2.
Bergamaschi G, Taris K, Biebricher A, Seymonson X, Witt H, Peterman E, et al.
Commun Biol
. 2024 Jun;
7(1):683.
PMID: 38834871
In the context of soft matter and cellular mechanics, microrheology - the use of micron-sized particles to probe the frequency-dependent viscoelastic response of materials - is widely used to shed...
3.
Spakman D, Clement T, Biebricher A, King G, Singh M, Hickson I, et al.
Nat Commun
. 2022 Nov;
13(1):7277.
PMID: 36433994
In anaphase, any unresolved DNA entanglements between the segregating sister chromatids can give rise to chromatin bridges. To prevent genome instability, chromatin bridges must be resolved prior to cytokinesis. The...
4.
Bogatyr V, Biebricher A, Bergamaschi G, Peterman E, Wuite G
ACS Nanosci Au
. 2022 Aug;
2(4):341-354.
PMID: 35996438
Studying cellular mechanics allows important insights into its cytoskeletal composition, developmental stage, and health. While many force spectroscopy assays exist that allow probing of mechanics of bioparticles, most of them...
5.
Bakx J, Biebricher A, King G, Christodoulis P, Sarlos K, Bizard A, et al.
Nat Commun
. 2022 Feb;
13(1):584.
PMID: 35102151
Topoisomerase IIIα is a type 1A topoisomerase that forms a complex with RMI1 and RMI2 called TRR in human cells. TRR plays an essential role in resolving DNA replication and...
6.
Backer A, King G, Biebricher A, Shepherd J, Noy A, Leake M, et al.
J Phys Chem B
. 2021 Jul;
125(30):8351-8361.
PMID: 34309392
The combination of DNA force spectroscopy and polarization microscopy of fluorescent DNA intercalator dyes can provide valuable insights into the structure of DNA under tension. These techniques have previously been...
7.
Spakman D, Bakx J, Biebricher A, Peterman E, Wuite G, King G
Nucleic Acids Res
. 2021 May;
49(10):5470-5492.
PMID: 33963870
Topoisomerases are essential enzymes that regulate DNA topology. Type 1A family topoisomerases are found in nearly all living organisms and are unique in that they require single-stranded (ss)DNA for activity....
8.
van Rosmalen M, Kamsma D, Biebricher A, Li C, Zlotnick A, Roos W, et al.
Sci Adv
. 2020 Jun;
6(16):eaaz1639.
PMID: 32494611
Many viruses use their genome as template for self-assembly into an infectious particle. However, this reaction remains elusive because of the transient nature of intermediate structures. To elucidate this process,...
9.
Meijering A, Biebricher A, Sitters G, Brouwer I, Peterman E, Wuite G, et al.
Nucleic Acids Res
. 2020 Feb;
48(6):e34.
PMID: 32016413
Fluorescence microscopy is invaluable to a range of biomolecular analysis approaches. The required labeling of proteins of interest, however, can be challenging and potentially perturb biomolecular functionality as well as...
10.
Backer A, Biebricher A, King G, Wuite G, Heller I, Peterman E
Sci Adv
. 2019 Mar;
5(3):eaav1083.
PMID: 30915395
DNA structural transitions facilitate genomic processes, mediate drug-DNA interactions, and inform the development of emerging DNA-based biotechnology such as programmable materials and DNA origami. While some features of DNA conformational...