Erin K Shanle
Overview
Explore the profile of Erin K Shanle including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
19
Citations
783
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Harris C, Savas J, Ray S, Shanle E
Mol Biol Rep
. 2021 Jun;
48(5):4107-4119.
PMID: 34075539
DNA damage response (DDR) pathways are initiated to prevent mutations from being passed on in the event of DNA damage. Mutations in DDR proteins can contribute to the development and...
2.
Slaughter M, Shanle E, Khan A, Chua K, Hong T, Boxer L, et al.
Cell Rep
. 2021 Jan;
34(3):108638.
PMID: 33472068
Histone acetylation levels are regulated by histone acetyltransferases (HATs) and histone deacetylases (HDACs) that antagonistically control the overall balance of this post-translational modification. HDAC inhibitors (HDACi) are potent agents that...
3.
Shanle E, Trubitsyn D
J Microbiol Biol Educ
. 2020 Dec;
21(3).
PMID: 33294096
No abstract available.
4.
Slaughter M, Shanle E, McFadden A, Hollis E, Suttle L, Strahl B, et al.
J Biol Chem
. 2018 Jul;
293(35):13592-13603.
PMID: 29986887
Chromatin remodelers use bromodomains (BDs) to recognize histones. Polybromo 1 (PBRM1 or BAF180) is hypothesized to function as the nucleosome-recognition subunit of the PBAF chromatin-remodeling complex and is frequently mutated...
5.
Shanle E, Shinsky S, Bridgers J, Bae N, Sagum C, Krajewski K, et al.
Epigenetics Chromatin
. 2017 Mar;
10:12.
PMID: 28293301
Background: Histone posttranslational modifications (PTMs) function to regulate chromatin structure and function in part through the recruitment of effector proteins that harbor specialized "reader" domains. Despite efforts to elucidate reader...
6.
Savitsky P, Krojer T, Fujisawa T, Lambert J, Picaud S, Wang C, et al.
Cell Rep
. 2016 Dec;
17(10):2724-2737.
PMID: 27926874
Elucidation of interactions involving DNA and histone post-translational-modifications (PTMs) is essential for providing insights into complex biological functions. Reader assemblies connected by flexible linkages facilitate avidity and increase affinity; however,...
7.
Andrews F, Shinsky S, Shanle E, Bridgers J, Gest A, Tsun I, et al.
Nat Chem Biol
. 2016 Apr;
12(6):396-8.
PMID: 27089029
The discovery of new histone modifications is unfolding at startling rates; however, the identification of effectors capable of interpreting these modifications has lagged behind. Here we report the YEATS domain...
8.
Andrews F, Shanle E, Strahl B, Kutateladze T
Transcription
. 2016 Mar;
7(1):14-20.
PMID: 26934307
The YEATS domains of AF9 and Taf14 have recently been found to recognize the histone H3K9ac modification. In this commentary, we discuss the mechanistic and biological implications of this interaction....
9.
Shanle E, Tsun I, Strahl B
Biochem Mol Biol Educ
. 2015 Nov;
44(1):68-74.
PMID: 26537758
Course-based undergraduate research experiences (CUREs) provide an opportunity for students to engage in experiments with outcomes that are unknown to both the instructor and students. These experiences allow students and...
10.
Shanle E, Andrews F, Meriesh H, McDaniel S, Dronamraju R, DiFiore J, et al.
Genes Dev
. 2015 Sep;
29(17):1795-800.
PMID: 26341557
The YEATS domain, found in a number of chromatin-associated proteins, has recently been shown to have the capacity to bind histone lysine acetylation. Here, we show that the YEATS domain...